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Table 1 Enriched categories – genes significantly up- or down-regulated at 3 months (but not significant at 5 or 8 months)

From: Gene expression profiling in a mouse model of infantile neuronal ceroid lipofuscinosis reveals upregulation of immediate early genes and mediators of the inflammatory response

Enriched Category (p-value) Subcategory Examples 3 mo 5 mo 8 mo
    (-fold change)
Pattern Specification (p < 0.0023) Immediate early genes aArc 3.5 2.7 1.0
   aCysteine-rich protein 61 3.0 1.8 4.5
   Zbtb16 -2.4 -1.3 1.8
Transcription (p < 0.015) Immediate early genes ac-Fos 2.9 3.6 2.4
   btg2 2.7 1.2 1.1
   aNR4A1 2.3 2.1 -1.1
   aJun-b 1.7 1.9 1.5
Response to DNA Damage Stimulus (p < 0.021) DNA replication and stress response hmg2 2.0 1.3 2.2
   PCNA -1.8 1.1 1.1
   Sgk1 -2.3 1.1 2.4
  1. aReported to be immediate-early response genes expressed in central nervous system