TY - JOUR AU - Mukherjee, S. P. AU - Lane, R. H. AU - Lynn, W. S. PY - 1978 DA - 1978// TI - Endogenous hydrogen peroxide and peroxidative metabolism in adipocytes in response to insulin and sulfhydryl reagents JO - Biochem Pharmacol VL - 27 UR - https://doi.org/10.1016/0006-2952(78)90332-5 DO - 10.1016/0006-2952(78)90332-5 ID - Mukherjee1978 ER - TY - JOUR AU - May, J. M. AU - de Haen, C. PY - 1979 DA - 1979// TI - Insulin-stimulated intracellular hydrogen peroxide production in rat epididymal fat cells JO - J Biol Chem VL - 254 ID - May1979 ER - TY - JOUR AU - Goldstein, B. J. AU - Mahadev, K. AU - Wu, X. AU - Zhu, L. AU - Motoshima, H. PY - 2005 DA - 2005// TI - Role of insulin-induced reactive oxygen species in the insulin signaling pathway JO - Antioxid Redox Signal VL - 7 UR - https://doi.org/10.1089/ars.2005.7.1021 DO - 10.1089/ars.2005.7.1021 ID - Goldstein2005 ER - TY - JOUR AU - Goldstein, B. J. AU - Mahadev, K. AU - Wu, X. PY - 2005 DA - 2005// TI - Redox paradox: insulin action is facilitated by insulin-stimulated reactive oxygen species with multiple potential signaling targets JO - Diabetes VL - 54 UR - https://doi.org/10.2337/diabetes.54.2.311 DO - 10.2337/diabetes.54.2.311 ID - Goldstein2005 ER - TY - JOUR AU - Schmid, E. AU - El Benna, J. AU - Galter, D. AU - Klein, G. AU - Droge, W. PY - 1998 DA - 1998// TI - Redox priming of the insulin receptor β-chain associated with altered tyrosine kinase activity and insulin responsiveness in the absence of tyrosine autophosphorylation JO - FASEB J VL - 12 ID - Schmid1998 ER - TY - JOUR AU - Schmid, E. AU - Hotz-Wagenblatt, A. AU - Hack, V. AU - Droge, W. PY - 1999 DA - 1999// TI - Phosphorylation of the insulin receptor kinase by phosphocreatine in combination with hydrogen peroxide: the structural basis of redox priming JO - FASEB J VL - 13 ID - Schmid1999 ER - TY - JOUR AU - Schmitt, T. L. AU - Hotz-Wagenblatt, A. AU - Klein, H. AU - Droge, W. PY - 2005 DA - 2005// TI - Interdependent regulation of insulin receptor kinase activity by ADP and hydrogen peroxide JO - J Biol Chem VL - 280 UR - https://doi.org/10.1074/jbc.M410352200 DO - 10.1074/jbc.M410352200 ID - Schmitt2005 ER - TY - JOUR AU - Mahadev, K. AU - Zilbering, A. AU - Zhu, L. AU - Goldstein, B. J. PY - 2001 DA - 2001// TI - Insulin-stimulated hydrogen peroxide reversibly inhibits protein-tyrosine phosphatase 1b in vivo and enhances the early insulin action cascade JO - J Biol Chem VL - 276 UR - https://doi.org/10.1074/jbc.C100109200 DO - 10.1074/jbc.C100109200 ID - Mahadev2001 ER - TY - JOUR AU - Mahadev, K. AU - Wu, X. AU - Zilbering, A. AU - Zhu, L. AU - Lawrence, J. T. AU - Goldstein, B. J. PY - 2001 DA - 2001// TI - Hydrogen peroxide generated during cellular insulin stimulation is integral to activation of the distal insulin signaling cascade in 3T3-L1 adipocytes JO - J Biol Chem VL - 276 UR - https://doi.org/10.1074/jbc.M105061200 DO - 10.1074/jbc.M105061200 ID - Mahadev2001 ER - TY - JOUR AU - Meng, T. -. C. AU - Buckley, D. A. AU - Galic, S. AU - Tiganis, T. AU - Tonks, N. K. PY - 2004 DA - 2004// TI - Regulation of insulin signaling through reversible oxidation of the protein-tyrosine phosphatases TC45 and PTP1B JO - J Biol Chem VL - 279 UR - https://doi.org/10.1074/jbc.M404606200 DO - 10.1074/jbc.M404606200 ID - Meng2004 ER - TY - JOUR AU - Wu, X. AU - Zhu, L. AU - Zilbering, A. AU - Mahadev, K. AU - Motoshima, H. AU - Yao, J. AU - Goldstein, B. J. PY - 2005 DA - 2005// TI - Hyperglycemia potentiates H(2)O(2) production in adipocytes and enhances insulin signal transduction: potential role for oxidative inhibition of thiol-sensitive protein-tyrosine phosphatases JO - Antioxid Redox Signal VL - 7 UR - https://doi.org/10.1089/ars.2005.7.526 DO - 10.1089/ars.2005.7.526 ID - Wu2005 ER - TY - JOUR AU - Seo, J. H. AU - Ahn, Y. AU - Lee, S. R. AU - Yeol Yeo, C. AU - Chung Hur, K. PY - 2005 DA - 2005// TI - The major target of the endogenously generated reactive oxygen species in response to insulin stimulation is phosphatase and tensin homolog and not phosphoinositide-3 kinase (PI-3 kinase) in the PI-3 kinase/Akt pathway JO - Mol Biol Cell VL - 16 UR - https://doi.org/10.1091/mbc.E04-05-0369 DO - 10.1091/mbc.E04-05-0369 ID - Seo2005 ER - TY - JOUR AU - Mukherjee, S. P. AU - Lynn, W. S. PY - 1977 DA - 1977// TI - Reduced nicotinamide adenine dinucleotide phosphate oxidase in adipocyte plasma membrane and its activation by insulin. Possible role in the hormone's effects on adenylate cyclase and the hexose monophosphate shunt JO - Arch Biochem Biophys VL - 184 UR - https://doi.org/10.1016/0003-9861(77)90327-7 DO - 10.1016/0003-9861(77)90327-7 ID - Mukherjee1977 ER - TY - JOUR AU - Krieger-Brauer, H. I. AU - Kather, H. PY - 1992 DA - 1992// TI - Human fat cells possess a plasma membrane-bound H2O2-generating system that is activated by insulin via a mechanism bypassing the receptor kinase JO - J Clin Invest VL - 89 UR - https://doi.org/10.1172/JCI115641 DO - 10.1172/JCI115641 ID - Krieger-Brauer1992 ER - TY - JOUR AU - Krieger-Brauer, H. I. AU - Medda, P. K. AU - Kather, H. PY - 1997 DA - 1997// TI - Insulin-induced activation of NADPH-dependent H2O2 generation in human adipocyte plasma membranes is mediated by Galphai2 JO - J Biol Chem VL - 272 UR - https://doi.org/10.1074/jbc.272.15.10135 DO - 10.1074/jbc.272.15.10135 ID - Krieger-Brauer1997 ER - TY - JOUR AU - Kreuzer, J. AU - Nurnberg, B. AU - Krieger-Brauer, H. I. PY - 2004 DA - 2004// TI - Ligand-dependent autophosphorylation of the insulin receptor is positively regulated by Gi-proteins JO - Biochem J VL - 380 UR - https://doi.org/10.1042/bj20031659 DO - 10.1042/bj20031659 ID - Kreuzer2004 ER - TY - JOUR AU - Mahadev, K. AU - Motoshima, H. AU - Wu, X. AU - Ruddy, J. M. AU - Arnold, R. S. AU - Cheng, G. AU - Lambeth, J. D. AU - Goldstein, B. J. PY - 2004 DA - 2004// TI - The NAD(P)H oxidase homolog Nox4 modulates insulin-stimulated generation of H2O2 and plays an integral role in insulin signal transduction JO - Mol Cell Biol VL - 24 UR - https://doi.org/10.1128/MCB.24.5.1844-1854.2004 DO - 10.1128/MCB.24.5.1844-1854.2004 ID - Mahadev2004 ER - TY - JOUR AU - Yang, M. AU - Yang, Y. AU - Zhang, S. AU - Kahn, A. M. PY - 2003 DA - 2003// TI - Insulin-stimulated hydrogen peroxide increases guanylate cyclase activity in vascular smooth muscle JO - Hypertension VL - 42 UR - https://doi.org/10.1161/01.HYP.0000092441.27668.BD DO - 10.1161/01.HYP.0000092441.27668.BD ID - Yang2003 ER - TY - JOUR AU - Yang, M. AU - Foster, E. AU - Kahn, A. M. PY - 2005 DA - 2005// TI - Insulin-stimulated NAD(P)H oxidase activity increases migration of cultured vascular smooth muscle cells JO - Am J Hypertens VL - 18 UR - https://doi.org/10.1016/j.amjhyper.2005.04.012 DO - 10.1016/j.amjhyper.2005.04.012 ID - Yang2005 ER - TY - JOUR AU - Pomytkin, I. A. AU - Kolesova, O. E. PY - 2002 DA - 2002// TI - Key role of succinate dehydrogenase in insulin-induced inactivation of protein tyrosine phosphatases JO - Bull Exp Biol Med VL - 133 UR - https://doi.org/10.1023/A:1020229724717 DO - 10.1023/A:1020229724717 ID - Pomytkin2002 ER - TY - JOUR AU - Pomytkin, I. A. AU - Kolesova, O. E. PY - 2003 DA - 2003// TI - Effect of insulin on the rate of hydrogen peroxide generation in mitochondria JO - Bull Exp Biol Med VL - 135 UR - https://doi.org/10.1023/A:1025412915297 DO - 10.1023/A:1025412915297 ID - Pomytkin2003 ER - TY - JOUR AU - Hwang, J. -. J. AU - Hur, K. C. PY - 2005 DA - 2005// TI - Insulin cannot activate extracellular-signal-related kinase due to inability to generate reactive oxygen species in SK-N-BE(2) human neuroblastoma cells JO - Mol Cells VL - 20 ID - Hwang2005 ER - TY - JOUR AU - Rosen, O. M. AU - Herrera, R. AU - Olowe, Y. AU - Petruzzelli, L. M. AU - Cobb, M. H. PY - 1983 DA - 1983// TI - Phosphorylation activates the insulin receptor tyrosine protein kinase JO - Proc Natl Acad Sci USA VL - 80 UR - https://doi.org/10.1073/pnas.80.11.3237 DO - 10.1073/pnas.80.11.3237 ID - Rosen1983 ER - TY - JOUR AU - Tornqvist, H. E. AU - Pierce, M. W. AU - Frackelton, A. R. AU - Nemenoff, R. A. AU - Avruch, J. PY - 1987 DA - 1987// TI - Identification of insulin receptor tyrosine residues autophosphorylated in vitro JO - J Biol Chem VL - 262 ID - Tornqvist1987 ER - TY - JOUR AU - White, M. F. AU - Shoelson, S. E. AU - Keutmann, H. AU - Kahn, C. R. PY - 1988 DA - 1988// TI - A cascade of tyrosine autophosphorylation in the β-subunit activates the phosphotransferase of the insulin receptor JO - J Biol Chem VL - 263 ID - White1988 ER - TY - JOUR AU - Zhang, B. AU - Tavare, J. M. AU - Ellis, L. AU - Roth, R. A. PY - 1991 DA - 1991// TI - The regulatory role of known tyrosine autophosphorylation sites of the insulin receptor kinase domain. An assessment by replacement with neutral and negatively charged amino acids JO - J Biol Chem VL - 266 ID - Zhang1991 ER - TY - JOUR AU - Tornqvist, H. E. AU - Gunsalus, J. R. AU - Nemenoff, R. A. AU - Frackelton, A. R. AU - Pierce, M. W. AU - Avruch, J. PY - 1988 DA - 1988// TI - Identification of the insulin receptor tyrosine residues undergoing insulin-stimulated phosphorylation in intact rat hepatoma cells JO - J Biol Chem VL - 263 ID - Tornqvist1988 ER - TY - JOUR AU - Issad, T. AU - Tavare, J. M. AU - Denton, R. M. PY - 1991 DA - 1991// TI - Analysis of insulin receptor phosphorylation sites in intact rat liver cells by two-dimensional phosphopeptide mapping. Predominance of the trisphosphorylated form of the kinase domain after stimulation by insulin JO - Biochem J VL - 275 UR - https://doi.org/10.1042/bj2750015 DO - 10.1042/bj2750015 ID - Issad1991 ER - TY - JOUR AU - Hubbard, S. R. AU - Wei, L. AU - Ellis, L. AU - Hendrickson, W. A. PY - 1994 DA - 1994// TI - Crystal structure of the tyrosine kinase domain of the human insulin receptor JO - Nature VL - 372 UR - https://doi.org/10.1038/372746a0 DO - 10.1038/372746a0 ID - Hubbard1994 ER - TY - JOUR AU - Hubbard, S. R. PY - 1997 DA - 1997// TI - Crystal structure of the activated insulin receptor tyrosine kinase in complex with peptide substrate and ATP analog JO - EMBO J VL - 16 UR - https://doi.org/10.1093/emboj/16.18.5572 DO - 10.1093/emboj/16.18.5572 ID - Hubbard1997 ER - TY - JOUR AU - Wie, L. AU - Hubbard, S. R. AU - Hendrickson, W. A. AU - Ellis, L. PY - 1995 DA - 1995// TI - Expression, Characterization, and Crystallization of the Catalytic Core of the Human Insulin Receptor Protein-tyrosine Kinase Domain JO - J Biol Chem VL - 270 UR - https://doi.org/10.1074/jbc.270.14.8122 DO - 10.1074/jbc.270.14.8122 ID - Wie1995 ER - TY - JOUR AU - Boveris, A. AU - Oshino, N. AU - Chance, B. PY - 1972 DA - 1972// TI - The cellular production of hydrogen peroxide JO - Biochem J VL - 128 UR - https://doi.org/10.1042/bj1280617 DO - 10.1042/bj1280617 ID - Boveris1972 ER - TY - JOUR AU - Votyakova, T. V. AU - Reynolds, I. J. PY - 2001 DA - 2001// TI - DeltaPsi(m)-Dependent and – independent production of reactive oxygen species by rat brain mitochondria JO - J Neurochem VL - 79 UR - https://doi.org/10.1046/j.1471-4159.2001.00548.x DO - 10.1046/j.1471-4159.2001.00548.x ID - Votyakova2001 ER - TY - JOUR AU - Loschen, G. AU - Azzi, A. AU - Richter, C. AU - Flohe, L. PY - 1974 DA - 1974// TI - Superoxide radicals as precursors of mitochondrial hydrogen peroxide JO - FEBS Lett VL - 42 UR - https://doi.org/10.1016/0014-5793(74)80281-4 DO - 10.1016/0014-5793(74)80281-4 ID - Loschen1974 ER - TY - JOUR AU - Korshunov, S. S. AU - Skulachev, V. P. AU - Starkov, A. A. PY - 1997 DA - 1997// TI - High protonic potential actuates a mechanism of production of reactive oxygen species in mitochondria JO - FEBS Lett VL - 416 UR - https://doi.org/10.1016/S0014-5793(97)01159-9 DO - 10.1016/S0014-5793(97)01159-9 ID - Korshunov1997 ER - TY - JOUR AU - Korshunov, S. S. AU - Korkina, O. V. AU - Ruuge, E. K. AU - Skulachev, V. P. AU - Starkov, A. A. PY - 1998 DA - 1998// TI - Fatty acids as natural uncouplers preventing generation of O2.- and H2O2 by mitochondria in the resting state JO - FEBS Lett VL - 435 UR - https://doi.org/10.1016/S0014-5793(98)01073-4 DO - 10.1016/S0014-5793(98)01073-4 ID - Korshunov1998 ER - TY - JOUR AU - Andreyev, A. Y. AU - Kushnareva, Y. E. AU - Starkov, A. A. PY - 2005 DA - 2005// TI - Mitochondrial metabolism of reactive oxygen species JO - Biochemistry (Mosc) VL - 70 UR - https://doi.org/10.1007/s10541-005-0102-7 DO - 10.1007/s10541-005-0102-7 ID - Andreyev2005 ER - TY - JOUR AU - Bessman, S. P. AU - Mohan, C. AU - Zaidise, I. PY - 1986 DA - 1986// TI - Intracellular site of insulin action: mitochondrial Krebs cycle JO - Proc Natl Acad Sci USA VL - 83 UR - https://doi.org/10.1073/pnas.83.14.5067 DO - 10.1073/pnas.83.14.5067 ID - Bessman1986 ER - TY - JOUR AU - Bessman, S. P. AU - Mohan, C. PY - 1997 DA - 1997// TI - Insulin as a probe of mitochondrial metabolism in situ JO - Mol Cell Biochem VL - 174 UR - https://doi.org/10.1023/A:1006834408181 DO - 10.1023/A:1006834408181 ID - Bessman1997 ER - TY - JOUR AU - Craft, S. PY - 2005 DA - 2005// TI - Insulin resistance syndrome and Alzheimer's disease: age- and obesity-related effects on memory, amyloid, and inflammation JO - Neurobiol Aging VL - 26 UR - https://doi.org/10.1016/j.neurobiolaging.2005.08.021 DO - 10.1016/j.neurobiolaging.2005.08.021 ID - Craft2005 ER - TY - JOUR AU - Hoyer, S. PY - 2004 DA - 2004// TI - Glucose metabolism and insulin receptor signal transduction in Alzheimer disease JO - Eur J Pharmacol VL - 490 UR - https://doi.org/10.1016/j.ejphar.2004.02.049 DO - 10.1016/j.ejphar.2004.02.049 ID - Hoyer2004 ER - TY - JOUR AU - de la Monte, S. M. AU - Wands, J. R. PY - 2005 DA - 2005// TI - Review of insulin and insulin-like growth factor expression, signaling, and malfunction in the central nervous system: Relevance to Alzheimer's disease JO - J Alzheimers Dis VL - 7 ID - de la Monte2005 ER - TY - JOUR AU - Steen, E. AU - Terry, B. M. AU - Rivera, E. J. AU - Cannon, J. L. AU - Neely, T. R. AU - Tavares, R. AU - Xu, X. J. AU - Wands, J. R. AU - de la Monte, S. M. PY - 2005 DA - 2005// TI - Impaired insulin and insulin-like growth factor expression and signaling mechanisms in Alzheimer's disease – is this type 3 diabetes? JO - J Alzheimers Dis VL - 7 ID - Steen2005 ER - TY - JOUR AU - Andreeva, N. AU - Khodorov, B. AU - Stelmashook, E. AU - Cragoe, E. AU - Victorov, I. PY - 1991 DA - 1991// TI - Inhibition of Na+/Ca2+ exchange enhances delayed neuronal death elicited by glutamate in cerebellar granule cell cultures JO - Brain Res VL - 548 UR - https://doi.org/10.1016/0006-8993(91)91141-M DO - 10.1016/0006-8993(91)91141-M ID - Andreeva1991 ER - TY - JOUR AU - Kiedrowski, L. AU - Brooker, G. AU - Costa, E. AU - Wroblewski, J. T. PY - 1994 DA - 1994// TI - Glutamate impairs neuronal calcium extrusion while reducing sodium gradient JO - Neuron VL - 12 UR - https://doi.org/10.1016/0896-6273(94)90272-0 DO - 10.1016/0896-6273(94)90272-0 ID - Kiedrowski1994 ER - TY - JOUR AU - Starkov, A. A. AU - Fiskum, G. AU - Chinopoulos, C. AU - Lorenzo, B. J. AU - Browne, S. E. AU - Patel, M. S. AU - Beal, M. F. PY - 2004 DA - 2004// TI - Mitochondrial alpha-ketoglutarate dehydrogenase complex generates reactive oxygen species JO - J Neurosci VL - 24 UR - https://doi.org/10.1523/JNEUROSCI.1899-04.2004 DO - 10.1523/JNEUROSCI.1899-04.2004 ID - Starkov2004 ER -