Skip to main content

Table 1 Comparison of extracellular levels (Cext, i.e. Cin = Cout), microdialysate concentrations (Cdial, i.e. Cin = 0 mol/L), and in vivo extraction efficiency (Ed) i.e. slope of Cin-Cout vs Cin) of GLU and GABA determined by the "no net flux" method (for details, see Methods) in absence epilepsy rats (GAERS strain) and non-epileptic Wistar (NEC) rats

From: Glutamatergic alterations in the cortex of genetic absence epilepsy rats

 

GLU (μmol/L)

GABA (nmol/L)

 

GAERS

NEC

GAERS

NEC

Cortex

(5)

(5)

(5)

(5)

Cext

1.67 ± 0.44

0.91 ± 0.01

18.1 ± 8.1

16 ± 6.1

Cdial

0.78 ± 0.10

0.68 ± 0.1

10 ± 3.0

12.5 ± 4.2

Ed

0.59 ± 0.18

0.76 ± 0.10

0.67 ± 0.12

0.82 ± 0.05

Thalamus

(5)

(6)

(5)

(6)

Cext

3.31 ± 146

4.82 ± 1.90

18.5 ± 4.4

14.1 ± 1.9

Cdial

1.94 ± 0.78

2.26 ± 0.96

15.0 ± 3.3

12.5 ± 2.4

Ed

0.63 ± 0.1

0.47 ± 0.08

0.83 ± 0.05

0.87 ± 0.09

  1. Number of rats per group in brackets