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Table 1 Comparison of extracellular levels (Cext, i.e. Cin = Cout), microdialysate concentrations (Cdial, i.e. Cin = 0 mol/L), and in vivo extraction efficiency (Ed) i.e. slope of Cin-Cout vs Cin) of GLU and GABA determined by the "no net flux" method (for details, see Methods) in absence epilepsy rats (GAERS strain) and non-epileptic Wistar (NEC) rats

From: Glutamatergic alterations in the cortex of genetic absence epilepsy rats

  GLU (μmol/L) GABA (nmol/L)
  GAERS NEC GAERS NEC
Cortex (5) (5) (5) (5)
Cext 1.67 ± 0.44 0.91 ± 0.01 18.1 ± 8.1 16 ± 6.1
Cdial 0.78 ± 0.10 0.68 ± 0.1 10 ± 3.0 12.5 ± 4.2
Ed 0.59 ± 0.18 0.76 ± 0.10 0.67 ± 0.12 0.82 ± 0.05
Thalamus (5) (6) (5) (6)
Cext 3.31 ± 146 4.82 ± 1.90 18.5 ± 4.4 14.1 ± 1.9
Cdial 1.94 ± 0.78 2.26 ± 0.96 15.0 ± 3.3 12.5 ± 2.4
Ed 0.63 ± 0.1 0.47 ± 0.08 0.83 ± 0.05 0.87 ± 0.09
  1. Number of rats per group in brackets