Figure 3
From: Sodium channel Nav1.6 accumulates at the site of infraorbital nerve injury
Results of quantitative analyses performed in normal (N) and lesioned (L) infraorbital nerves. A and B. The density (A) and average pixel size (B) of Nav1.6 accumulations (with a size of ≥ 15 pixels) was significantly greater in lesioned IONs than seen in normal IONs. C. The average immunofluorescence intensity (0–65,535 range) of pixels with Nav1.6 staining located in caspr-identified typical nodes was significantly greater in lesioned IONs when compared to normal IONs. D. The average axial length (in pixels) of the nodal gap within caspr-identified typical nodal accumulations was significantly greater in lesioned IONs when compared to normal IONs. E. The average immunofluorescence intensity (0–65,535 range) of pixels with caspr staining located within the paranodal regions of caspr-identified typical nodes was significantly greater in normal IONs when compared to lesioned IONs.