Figure 6

Immunohistochemical staining of microdystrophin in the diaphragm muscle from mdx mouse injected intraperitoneally with pAMICDYS or pAVP22-MICDYS. The diaphragm muscle with C57BL/10 mouse (A); the diaphragm muscle with mdx mouse treated by pAVP22-MICDYS (B); treated by pAMICDYS (C). Microdystrophin -positive fibers were only detected in groups injected by pAVP22-MICDYS, not in groups injected by pAMICDYS. Magnification: × 100.