Distribution of TRPM5-immunoreactive cells in the mouse gastrointestinal tract. Confocal images of TRPM5-specific signals (left panel) and their overlay with the corresponding DIC images (right panel) are depicted. (A, B) TRPM5-expressing cells are abundant in the cardiac region of the stomach. In gut epithelia, TRPM5-enriched cells are detected in the duodenal villi (C, D), the ileum (E, F) and the colon (G, H). Scale bars are 20 μm.