Figure 3From: Modulatory effects of nitric oxide-active drugs on the anticonvulsant activity of lamotrigine in an experimental model of partial complex epilepsy in the ratEffects of 7-Nitroindazole, L-arginine and Lamotrigine administration alone and in combination on MDA latency. Effects of 7-Nitroindazole (75 mg kg-1 i.p.), L-arginine (1 g kg-1 i.p.) and Lamotrigine (10 mg kg-1 i.p.) administration alone and in combination on MDA latency (n = 10 rats for each treatment). In abscissa the progressive number of train of stimuli applied every 10 min is indicated. Asterisks between lines (-*-) indicate a significant difference between the two treatments (P < 0.05).Back to article page