Figure 3
From: Reduced expression of TAC1, PENK and SOCS2 in Hcrtr-2 mutated narcoleptic dog brain
Expression differences between narcoleptic and heterozygous dogs, determined by qPCR. Mean expression of A) PENK, B) TAC1 and C) SOCS2 in six narcoleptic dogs (black bars) and six unaffected siblings (grey bars) heterozygous for the canarc-1 mutation with standard errors given. Narcoleptic individuals show an overall restricted expression pattern for the three genes (PENK p = 0.037, TAC1 p = 0.047 and SOCS2 p = 0.057), with most pronounced effect in the amygdala.