TY - JOUR AU - Small, D. H. AU - Mok, S. S. AU - Bornstein, J. C. PY - 2001 DA - 2001// TI - Alzheimer's disease and abeta toxicity: from top to bottom JO - Nat Rev Neurosci VL - 2 UR - https://doi.org/10.1038/35086072 DO - 10.1038/35086072 ID - Small2001 ER - TY - JOUR AU - Glenner, G. G. AU - Wong, C. W. PY - 1984 DA - 1984// TI - Alzheimer's disease: initial report of the purification and characterization of a novel cerebrovascular amyloid protein JO - Biochem Biophys Res Commun VL - 120 UR - https://doi.org/10.1016/S0006-291X(84)80190-4 DO - 10.1016/S0006-291X(84)80190-4 ID - Glenner1984 ER - TY - JOUR AU - Koo, E. H. AU - Squazzo, S. L. PY - 1994 DA - 1994// TI - Evidence that production and release of amyloid beta-protein involves the endocytic pathway JO - J Biol Chem VL - 269 ID - Koo1994 ER - TY - JOUR AU - Perez, R. G. AU - Squazzo, S. L. AU - Koo, E. H. PY - 1996 DA - 1996// TI - Enhanced release of amyloid beta-protein from codon 670/671 "swedish" mutant beta-amyloid precursor protein occurs in both secretory and endocytic pathways JO - J Biol Chem VL - 271 UR - https://doi.org/10.1074/jbc.271.15.9100 DO - 10.1074/jbc.271.15.9100 ID - Perez1996 ER - TY - JOUR AU - Caporaso, G. L. AU - Gandy, S. E. AU - Buxbaum, J. D. AU - Greengard, P. PY - 1992 DA - 1992// TI - Chloroquine inhibits intracellular degradation but not secretion of alzheimer beta/a4 amyloid precursor protein JO - Proc Natl Acad Sci USA VL - 89 UR - https://doi.org/10.1073/pnas.89.6.2252 DO - 10.1073/pnas.89.6.2252 ID - Caporaso1992 ER - TY - JOUR AU - Shoji, M. AU - Golde, T. E. AU - Ghiso, J. AU - Cheung, T. T. AU - Estus, S. AU - Shaffer, L. M. AU - Cai, X. D. AU - McKay, D. M. AU - Tintner, R. AU - Frangione, B. PY - 1992 DA - 1992// TI - Production of the alzheimer amyloid beta protein by normal proteolytic processing JO - Science VL - 258 UR - https://doi.org/10.1126/science.1439760 DO - 10.1126/science.1439760 ID - Shoji1992 ER - TY - JOUR AU - Daugherty, B. L. AU - Green, S. A. PY - 2001 DA - 2001// TI - Endosomal sorting of amyloid precursor protein-p-selectin chimeras influences secretase processing JO - Traffic VL - 2 UR - https://doi.org/10.1034/j.1600-0854.2001.21206.x DO - 10.1034/j.1600-0854.2001.21206.x ID - Daugherty2001 ER - TY - JOUR AU - Xia, W. AU - Ray, W. J. AU - Ostaszewski, B. L. AU - Rahmati, T. AU - Kimberly, W. T. AU - Wolfe, M. S. AU - Zhang, J. AU - Goate, A. M. AU - Selkoe, D. J. PY - 2000 DA - 2000// TI - Presenilin complexes with the c-terminal fragments of amyloid precursor protein at the sites of amyloid beta-protein generation JO - Proc Natl Acad Sci USA VL - 97 UR - https://doi.org/10.1073/pnas.97.16.9299 DO - 10.1073/pnas.97.16.9299 ID - Xia2000 ER - TY - JOUR AU - Haass, C. AU - Steiner, H. PY - 2002 DA - 2002// TI - Alzheimer disease gamma-secretase: a complex story of gxgd-type presenilin proteases JO - Trends Cell Biol VL - 12 UR - https://doi.org/10.1016/S0962-8924(02)02394-2 DO - 10.1016/S0962-8924(02)02394-2 ID - Haass2002 ER - TY - JOUR AU - Koo, E. H. AU - Squazzo, S. L. AU - Selkoe, D. J. AU - Koo, C. H. PY - 1996 DA - 1996// TI - Trafficking of cell-surface amyloid beta-protein precursor. i. secretion, endocytosis and recycling as detected by labeled monoclonal antibody JO - J Cell Sci VL - 109 ID - Koo1996 ER - TY - JOUR AU - Peraus, G. C. AU - Masters, C. L. AU - Beyreuther, K. PY - 1997 DA - 1997// TI - Late compartments of amyloid precursor protein transport in sy5y cells are involved in beta-amyloid secretion JO - J Neurosci VL - 17 ID - Peraus1997 ER - TY - JOUR AU - Soriano, S. AU - Chyung, A. S. AU - Chen, X. AU - Stokin, G. B. AU - Lee, V. M. AU - Koo, E. H. PY - 1999 DA - 1999// TI - Expression of beta-amyloid precursor protein-cd3gamma chimeras to demonstrate the selective generation of amyloid beta(1–40) and amyloid beta(1–42) peptides within secretory and endocytic compartments JO - J Biol Chem VL - 274 UR - https://doi.org/10.1074/jbc.274.45.32295 DO - 10.1074/jbc.274.45.32295 ID - Soriano1999 ER - TY - JOUR AU - Haass, C. AU - Koo, E. H. AU - Mellon, A. AU - Hung, A. Y. AU - Selkoe, D. J. PY - 1992 DA - 1992// TI - Targeting of cell-surface beta-amyloid precursor protein to lysosomes: alternative processing into amyloid-bearing fragments JO - Nature VL - 357 UR - https://doi.org/10.1038/357500a0 DO - 10.1038/357500a0 ID - Haass1992 ER - TY - JOUR AU - Yang, A. J. AU - Chandswangbhuvana, D. AU - Margol, L. AU - Glabe, C. G. PY - 1998 DA - 1998// TI - Loss of endosomal/lysosomal membrane impermeability is an early event in amyloid abeta1-42 pathogenesis JO - J Neurosci Res VL - 52 UR - https://doi.org/3.0.CO;2-3 DO - 3.0.CO;2-3 ID - Yang1998 ER - TY - JOUR AU - Kirkitadze, M. D. AU - Condron, M. M. AU - Teplow, D. B. PY - 2001 DA - 2001// TI - Identification and characterization of key kinetic intermediates in amyloid beta-protein fibrillogenesis JO - J Mol Biol VL - 312 UR - https://doi.org/10.1006/jmbi.2001.4970 DO - 10.1006/jmbi.2001.4970 ID - Kirkitadze2001 ER - TY - JOUR AU - Gorman, P. M. AU - Yip, C. M. AU - Fraser, P. E. AU - Chakrabartty, A. PY - 2003 DA - 2003// TI - Alternate aggregation pathways of the alzheimer beta-amyloid peptide: abeta association kinetics at endosomal ph JO - J Mol Biol VL - 325 UR - https://doi.org/10.1016/S0022-2836(02)01279-2 DO - 10.1016/S0022-2836(02)01279-2 ID - Gorman2003 ER - TY - JOUR AU - Stine, W. B. J. AU - Snyder, S. W. AU - Ladror, U. S. AU - Wade, W. S. AU - Miller, M. F. AU - Perun, T. J. AU - Holzman, T. F. AU - Krafft, G. A. PY - 1996 DA - 1996// TI - The nanometer-scale structure of amyloid-beta visualized by atomic force microscopy JO - J Protein Chem VL - 15 UR - https://doi.org/10.1007/BF01887400 DO - 10.1007/BF01887400 ID - Stine1996 ER - TY - JOUR AU - Lambert, M. P. AU - Barlow, A. K. AU - Chromy, B. A. AU - Edwards, C. AU - Freed, R. AU - Liosatos, M. AU - Morgan, T. E. AU - Rozovsky, I. AU - Trommer, B. AU - Viola, K. L. AU - Wals, P. AU - Zhang, C. AU - Finch, C. E. AU - Krafft, G. A. AU - Klein, W. L. PY - 1998 DA - 1998// TI - Diffusible, nonfibrillar ligands derived from abeta1–42 are potent central nervous system neurotoxins JO - Proc Natl Acad Sci USA VL - 95 UR - https://doi.org/10.1073/pnas.95.11.6448 DO - 10.1073/pnas.95.11.6448 ID - Lambert1998 ER - TY - JOUR AU - Huang, T. H. AU - Yang, D. S. AU - Plaskos, N. P. AU - Go, S. AU - Yip, C. M. AU - Fraser, P. E. AU - Chakrabartty, A. PY - 2000 DA - 2000// TI - Structural studies of soluble oligomers of the alzheimer beta-amyloid peptide JO - J Mol Biol VL - 297 UR - https://doi.org/10.1006/jmbi.2000.3559 DO - 10.1006/jmbi.2000.3559 ID - Huang2000 ER - TY - JOUR AU - Podlisny, M. B. AU - Walsh, D. M. AU - Amarante, P. AU - Ostaszewski, B. L. AU - Stimson, E. R. AU - Maggio, J. E. AU - Teplow, D. B. AU - Selkoe, D. J. PY - 1998 DA - 1998// TI - Oligomerization of endogenous and synthetic amyloid beta-protein at nanomolar levels in cell culture and stabilization of monomer by congo red JO - Biochemistry VL - 37 UR - https://doi.org/10.1021/bi972029u DO - 10.1021/bi972029u ID - Podlisny1998 ER - TY - JOUR AU - Walsh, D. M. AU - Hartley, D. M. AU - Kusumoto, Y. AU - Fezoui, Y. AU - Condron, M. M. AU - Lomakin, A. AU - Benedek, G. B. AU - Selkoe, D. J. AU - Teplow, D. B. PY - 1999 DA - 1999// TI - Amyloid beta-protein fibrillogenesis. structure and biological activity of protofibrillar intermediates JO - J Biol Chem VL - 274 UR - https://doi.org/10.1074/jbc.274.36.25945 DO - 10.1074/jbc.274.36.25945 ID - Walsh1999 ER - TY - JOUR AU - Selkoe, D. J. PY - 1989 DA - 1989// TI - The deposition of amyloid proteins in the aging mammalian brain: implications for alzheimer's disease JO - Ann Med VL - 21 UR - https://doi.org/10.3109/07853898909149187 DO - 10.3109/07853898909149187 ID - Selkoe1989 ER - TY - JOUR AU - Mrak, R. E. AU - Griffinbc, W. S. PY - 2001 DA - 2001// TI - The role of activated astrocytes and of the neurotrophic cytokine s100b in the pathogenesis of alzheimer's disease JO - Neurobiol Aging VL - 22 UR - https://doi.org/10.1016/S0197-4580(01)00293-7 DO - 10.1016/S0197-4580(01)00293-7 ID - Mrak2001 ER - TY - JOUR AU - Pike, C. J. AU - Burdick, D. AU - Walencewicz, A. J. AU - Glabe, C. G. AU - Cotman, C. W. PY - 1993 DA - 1993// TI - Neurodegeneration induced by beta-amyloid peptides in vitro: the role of peptide assembly state JO - J Neurosci VL - 13 ID - Pike1993 ER - TY - JOUR AU - Simmons, L. K. AU - May, P. C. AU - Tomaselli, K. J. AU - Rydel, R. E. AU - Fuson, K. S. AU - Brigham, E. F. AU - Wright, S. AU - Lieberburg, I. AU - Becker, G. W. AU - Brems, D. N. PY - 1994 DA - 1994// TI - Secondary structure of amyloid beta peptide correlates with neurotoxic activity in vitro JO - Mol Pharmacol VL - 45 ID - Simmons1994 ER - TY - JOUR AU - Lorenzo, A. AU - Yankner, B. A. PY - 1994 DA - 1994// TI - Beta-amyloid neurotoxicity requires fibril formation and is inhibited by congo red JO - Proc Natl Acad Sci USA VL - 91 UR - https://doi.org/10.1073/pnas.91.25.12243 DO - 10.1073/pnas.91.25.12243 ID - Lorenzo1994 ER - TY - JOUR AU - Janus, C. AU - Pearson, J. AU - McLaurin, J. AU - Mathews, P. M. AU - Jiang, Y. AU - Schmidt, S. D. AU - Chishti, M. A. AU - Horne, P. AU - Heslin, D. AU - French, J. AU - Mount, H. T. AU - Nixon, R. A. AU - Mercken, M. AU - Bergeron, C. AU - Fraser, P. E. AU - St George-Hyslop, P. AU - Westaway, D. PY - 2000 DA - 2000// TI - A beta peptide immunization reduces behavioural impairment and plaques in a model of alzheimer's disease JO - Nature VL - 408 UR - https://doi.org/10.1038/35050110 DO - 10.1038/35050110 ID - Janus2000 ER - TY - JOUR AU - Morgan, D. AU - Diamond, D. M. AU - Gottschall, P. E. AU - Ugen, K. E. AU - Dickey, C. AU - Hardy, J. AU - Duff, K. AU - Jantzen, P. AU - DiCarlo, G. AU - Wilcock, D. AU - Connor, K. AU - Hatcher, J. AU - Hope, C. AU - Gordon, M. AU - Arendash, G. W. PY - 2000 DA - 2000// TI - A beta peptide vaccination prevents memory loss in an animal model of alzheimer's disease JO - Nature VL - 408 UR - https://doi.org/10.1038/35050116 DO - 10.1038/35050116 ID - Morgan2000 ER - TY - JOUR AU - Matsuoka, Y. AU - Saito, M. AU - LaFrancois, J. AU - Saito, M. AU - Gaynor, K. AU - Olm, V. AU - Wang, L. AU - Casey, E. AU - Lu, Y. AU - Shiratori, C. AU - Lemere, C. AU - Duff, K. PY - 2003 DA - 2003// TI - Novel therapeutic approach for the treatment of alzheimer's disease by peripheral administration of agents with an affinity to beta-amyloid JO - J Neurosci VL - 23 ID - Matsuoka2003 ER - TY - JOUR AU - Walsh, D. M. AU - Klyubin, I. AU - Fadeeva, J. V. AU - Cullen, W. K. AU - Anwyl, R. AU - Wolfe, M. S. AU - Rowan, M. J. AU - Selkoe, D. J. PY - 2002 DA - 2002// TI - Naturally secreted oligomers of amyloid beta protein potently inhibit hippocampal long-term potentiation in vivo JO - Nature VL - 416 UR - https://doi.org/10.1038/416535a DO - 10.1038/416535a ID - Walsh2002 ER - TY - JOUR AU - Hazum, E. AU - Cuatrecasas, P. AU - Marian, J. AU - Conn, P. M. PY - 1980 DA - 1980// TI - Receptor-mediated internalization of fluorescent gonadotropin-releasing hormone by pituitary gonadotropes JO - Proc Natl Acad Sci USA VL - 77 UR - https://doi.org/10.1073/pnas.77.11.6692 DO - 10.1073/pnas.77.11.6692 ID - Hazum1980 ER - TY - BOOK AU - Slavik, J. PY - 1994 DA - 1994// TI - Fluorescent probes in cellular and moecular biology ID - Slavik1994 ER - TY - BOOK AU - Stevens, J. AU - Mills, L. AU - Trogadis, J. PY - 1994 DA - 1994// TI - Three-dimensional confocal microscopy: volume investigation of biological specimens ID - Stevens1994 ER - TY - BOOK AU - Slavi'k, J. PY - 1996 DA - 1996// TI - Fluorescence microscopy and fluorescent probes UR - https://doi.org/10.1007/978-1-4899-1866-6 DO - 10.1007/978-1-4899-1866-6 ID - Slavi'k1996 ER - TY - JOUR AU - Sengupta, P. AU - Garai, K. AU - Sahoo, B. AU - Shi, Y. AU - Callaway, D. J. E. AU - Maiti, S. PY - 2003 DA - 2003// TI - The amyloid beta peptide (abeta(1–40)) is thermodynamically soluble at physiological concentrations JO - Biochemistry VL - 42 UR - https://doi.org/10.1021/bi0341410 DO - 10.1021/bi0341410 ID - Sengupta2003 ER - TY - JOUR AU - Huang, T. H. AU - Fraser, P. E. AU - Chakrabartty, A. PY - 1997 DA - 1997// TI - Fibrillogenesis of alzheimer abeta peptides studied by fluorescence energy transfer JO - J Mol Biol VL - 269 UR - https://doi.org/10.1006/jmbi.1997.1050 DO - 10.1006/jmbi.1997.1050 ID - Huang1997 ER - TY - JOUR AU - Kheterpal, I. AU - Williams, A. AU - Murphy, C. AU - Bledsoe, B. AU - Wetzel, R. PY - 2001 DA - 2001// TI - Structural features of the abeta amyloid fibril elucidated by limited proteolysis JO - Biochemistry VL - 40 UR - https://doi.org/10.1021/bi010805z DO - 10.1021/bi010805z ID - Kheterpal2001 ER - TY - JOUR AU - Wurth, C. AU - Guimard, N. K. AU - Hecht, M. H. PY - 2002 DA - 2002// TI - Mutations that reduce aggregation of the alzheimer's abeta42 peptide: an unbiased search for the sequence determinants of abeta amyloidogenesis JO - J Mol Biol VL - 319 UR - https://doi.org/10.1016/S0022-2836(02)00399-6 DO - 10.1016/S0022-2836(02)00399-6 ID - Wurth2002 ER - TY - JOUR AU - LeVine, H. 3. PY - 1993 DA - 1993// TI - Thioflavine t interaction with synthetic alzheimer's disease beta-amyloid peptides: detection of amyloid aggregation in solution JO - Protein Sci VL - 2 UR - https://doi.org/10.1002/pro.5560020312 DO - 10.1002/pro.5560020312 ID - LeVine1993 ER - TY - JOUR AU - LeVine, H. 3. PY - 1999 DA - 1999// TI - Quantification of beta-sheet amyloid fibril structures with thioflavin t JO - Methods Enzymol VL - 309 UR - https://doi.org/10.1016/S0076-6879(99)09020-5 DO - 10.1016/S0076-6879(99)09020-5 ID - LeVine1999 ER - TY - JOUR AU - Kim, W. AU - Hecht, M. H. PY - 2005 DA - 2005// TI - Sequence determinants of enhanced amyloidogenicity of alzheimer a{beta}42 peptide relative to a{beta}40 JO - J Biol Chem VL - 280 UR - https://doi.org/10.1074/jbc.M505763200 DO - 10.1074/jbc.M505763200 ID - Kim2005 ER - TY - JOUR AU - Pawar, A. P. AU - Dubay, K. F. AU - Zurdo, J. AU - Chiti, F. AU - Vendruscolo, M. AU - Dobson, C. M. PY - 2005 DA - 2005// TI - Prediction of "aggregation-prone" and "aggregation-susceptible" regions in proteins associated with neurodegenerative diseases JO - J Mol Biol VL - 350 UR - https://doi.org/10.1016/j.jmb.2005.04.016 DO - 10.1016/j.jmb.2005.04.016 ID - Pawar2005 ER - TY - JOUR AU - Mazziotti, M. AU - Perlmutter, D. H. PY - 1998 DA - 1998// TI - Resistance to the apoptotic effect of aggregated amyloid-beta peptide in several different cell types including neuronal- and hepatoma-derived cell lines JO - Biochem J VL - 332 UR - https://doi.org/10.1042/bj3320517 DO - 10.1042/bj3320517 ID - Mazziotti1998 ER - TY - JOUR AU - Schmid, I. AU - Ferbas, J. AU - Uittenbogaart, C. H. AU - Giorgi, J. V. PY - 1999 DA - 1999// TI - Flow cytometric analysis of live cell proliferation and phenotype in populations with low viability JO - Cytometry VL - 35 UR - https://doi.org/3.0.CO;2-Y DO - 3.0.CO;2-Y ID - Schmid1999 ER - TY - JOUR AU - Gaforio, J. J. AU - Serrano, M. J. AU - Algarra, I. AU - Ortega, E. AU - Alvarez de Cienfuegos, G. PY - 2002 DA - 2002// TI - Phagocytosis of apoptotic cells assessed by flow cytometry using 7-aminoactinomycin d JO - Cytometry VL - 49 UR - https://doi.org/10.1002/cyto.10136 DO - 10.1002/cyto.10136 ID - Gaforio2002 ER - TY - JOUR AU - Nicolson, G. L. AU - Singer, S. J. PY - 1971 DA - 1971// TI - Ferritin-conjugated plant agglutinins as specific saccharide stains for electron microscopy: application to saccharides bound to cell membranes JO - Proc Natl Acad Sci USA VL - 68 UR - https://doi.org/10.1073/pnas.68.5.942 DO - 10.1073/pnas.68.5.942 ID - Nicolson1971 ER - TY - JOUR AU - Ivins, K. J. AU - Ivins, J. K. AU - Sharp, J. P. AU - Cotman, C. W. PY - 1999 DA - 1999// TI - Multiple pathways of apoptosis in pc12 cells. crma inhibits apoptosis induced by beta-amyloid JO - J Biol Chem VL - 274 UR - https://doi.org/10.1074/jbc.274.4.2107 DO - 10.1074/jbc.274.4.2107 ID - Ivins1999 ER - TY - JOUR AU - Schulz, J. G. AU - Megow, D. AU - Reszka, R. AU - Villringer, A. AU - Einhaupl, K. M. AU - Dirnagl, U. PY - 1998 DA - 1998// TI - Evidence that glypican is a receptor mediating beta-amyloid neurotoxicity in pc12 cells JO - Eur J Neurosci VL - 10 UR - https://doi.org/10.1046/j.1460-9568.1998.00220.x DO - 10.1046/j.1460-9568.1998.00220.x ID - Schulz1998 ER - TY - JOUR AU - Gowda, D. C. AU - Goossen, B. AU - Margolis, R. K. AU - Margolis, R. U. PY - 1989 DA - 1989// TI - Chondroitin sulfate and heparan sulfate proteoglycans of pc12 pheochromocytoma cells JO - J Biol Chem VL - 264 ID - Gowda1989 ER - TY - JOUR AU - van Engeland, M. AU - Nieland, L. J. AU - Ramaekers, F. C. AU - Schutte, B. AU - Reutelingsperger, C. P. PY - 1998 DA - 1998// TI - Annexin v-affinity assay: a review on an apoptosis detection system based on phosphatidylserine exposure JO - Cytometry VL - 31 UR - https://doi.org/3.0.CO;2-R DO - 3.0.CO;2-R ID - van Engeland1998 ER - TY - JOUR AU - Andree, H. A. AU - Reutelingsperger, C. P. AU - Hauptmann, R. AU - Hemker, H. C. AU - Hermens, W. T. AU - Willems, G. M. PY - 1990 DA - 1990// TI - Binding of vascular anticoagulant alpha (vac alpha) to planar phospholipid bilayers JO - J Biol Chem VL - 265 ID - Andree1990 ER - TY - JOUR AU - Hayashi, H. AU - Kimura, N. AU - Yamaguchi, H. AU - Hasegawa, K. AU - Yokoseki, T. AU - Shibata, M. AU - Yamamoto, N. AU - Michikawa, M. AU - Yoshikawa, Y. AU - Terao, K. AU - Matsuzaki, K. AU - Lemere, C. A. AU - Selkoe, D. J. AU - Naiki, H. AU - Yanagisawa, K. PY - 2004 DA - 2004// TI - A seed for alzheimer amyloid in the brain JO - J Neurosci VL - 24 UR - https://doi.org/10.1523/JNEUROSCI.0861-04.2004 DO - 10.1523/JNEUROSCI.0861-04.2004 ID - Hayashi2004 ER - TY - JOUR AU - McCann, J. A. AU - Mertz, J. A. AU - Czworkowski, J. AU - Picking, W. D. PY - 1997 DA - 1997// TI - Conformational changes in cholera toxin b subunit-ganglioside gm1 complexes are elicited by environmental ph and evoke changes in membrane structure JO - Biochemistry VL - 36 UR - https://doi.org/10.1021/bi962996p DO - 10.1021/bi962996p ID - McCann1997 ER - TY - JOUR AU - Kenworthy, A. K. AU - Petranova, N. AU - Edidin, M. PY - 2000 DA - 2000// TI - High-resolution fret microscopy of cholera toxin b-subunit and gpi-anchored proteins in cell plasma membranes JO - Mol Biol Cell VL - 11 UR - https://doi.org/10.1091/mbc.11.5.1645 DO - 10.1091/mbc.11.5.1645 ID - Kenworthy2000 ER - TY - JOUR AU - O'Hanlon, G. M. AU - Hirst, T. R. AU - Willison, H. J. PY - 2003 DA - 2003// TI - Ganglioside gm1 binding toxins and human neuropathy-associated igm antibodies differentially promote neuritogenesis in a pc12 assay JO - Neurosci Res VL - 47 UR - https://doi.org/10.1016/S0168-0102(03)00239-6 DO - 10.1016/S0168-0102(03)00239-6 ID - O'Hanlon2003 ER - TY - JOUR AU - Selkoe, D. J. PY - 2001 DA - 2001// TI - Alzheimer's disease: genes, proteins, and therapy JO - Physiol Rev VL - 81 ID - Selkoe2001 ER - TY - JOUR AU - Roher, A. E. AU - Lowenson, J. D. AU - Clarke, S. AU - Woods, A. S. AU - Cotter, R. J. AU - Gowing, E. AU - Ball, M. J. PY - 1993 DA - 1993// TI - Beta-amyloid-(1–42) is a major component of cerebrovascular amyloid deposits: implications for the pathology of alzheimer disease JO - Proc Natl Acad Sci USA VL - 90 UR - https://doi.org/10.1073/pnas.90.22.10836 DO - 10.1073/pnas.90.22.10836 ID - Roher1993 ER - TY - JOUR AU - Gravina, S. A. AU - Ho, L. AU - Eckman, C. B. AU - Long, K. E. AU - Otvos, L. J. AU - Younkin, L. H. AU - Suzuki, N. AU - Younkin, S. G. PY - 1995 DA - 1995// TI - Amyloid beta protein (a beta) in alzheimer's disease brain. biochemical and immunocytochemical analysis with antibodies specific for forms ending at a beta 40 or a beta 42(43) JO - J Biol Chem VL - 270 UR - https://doi.org/10.1074/jbc.270.13.7013 DO - 10.1074/jbc.270.13.7013 ID - Gravina1995 ER - TY - JOUR AU - Price, D. L. AU - Sisodia, S. S. PY - 1998 DA - 1998// TI - Mutant genes in familial alzheimer's disease and transgenic models JO - Annu Rev Neurosci VL - 21 UR - https://doi.org/10.1146/annurev.neuro.21.1.479 DO - 10.1146/annurev.neuro.21.1.479 ID - Price1998 ER - TY - JOUR AU - Klunk, W. E. AU - Bacskai, B. J. AU - Mathis, C. A. AU - Kajdasz, S. T. AU - McLellan, M. E. AU - Frosch, M. P. AU - Debnath, M. L. AU - Holt, D. P. AU - Wang, Y. AU - Hyman, B. T. PY - 2002 DA - 2002// TI - Imaging abeta plaques in living transgenic mice with multiphoton microscopy and methoxy-x04, a systemically administered congo red derivative JO - J Neuropathol Exp Neurol VL - 61 UR - https://doi.org/10.1093/jnen/61.9.797 DO - 10.1093/jnen/61.9.797 ID - Klunk2002 ER - TY - JOUR AU - Kung, M. AU - Hou, C. AU - Zhuang, Z. AU - Zhang, B. AU - Skovronsky, D. AU - Trojanowski, J. Q. AU - Lee, V. M. AU - Kung, H. F. PY - 2002 DA - 2002// TI - Impy: an improved thioflavin-t derivative for in vivo labeling of beta-amyloid plaques JO - Brain Res VL - 956 UR - https://doi.org/10.1016/S0006-8993(02)03436-4 DO - 10.1016/S0006-8993(02)03436-4 ID - Kung2002 ER - TY - JOUR AU - Maggio, J. E. AU - Stimson, E. R. AU - Ghilardi, J. R. AU - Allen, C. J. AU - Dahl, C. E. AU - Whitcomb, D. C. AU - Vigna, S. R. AU - Vinters, H. V. AU - Labenski, M. E. AU - Mantyh, P. W. PY - 1992 DA - 1992// TI - Reversible in vitro growth of alzheimer disease beta-amyloid plaques by deposition of labeled amyloid peptide JO - Proc Natl Acad Sci USA VL - 89 UR - https://doi.org/10.1073/pnas.89.12.5462 DO - 10.1073/pnas.89.12.5462 ID - Maggio1992 ER - TY - JOUR AU - Burdick, D. AU - Kosmoski, J. AU - Knauer, M. F. AU - Glabe, C. G. PY - 1997 DA - 1997// TI - Preferential adsorption, internalization and resistance to degradation of the major isoform of the alzheimer's amyloid peptide, a beta 1–42, in differentiated pc12 cells JO - Brain Res VL - 746 UR - https://doi.org/10.1016/S0006-8993(96)01262-0 DO - 10.1016/S0006-8993(96)01262-0 ID - Burdick1997 ER - TY - JOUR AU - Lambert, M. P. AU - Viola, K. L. AU - Chromy, B. A. AU - Chang, L. AU - Morgan, T. E. AU - Yu, J. AU - Venton, D. L. AU - Krafft, G. A. AU - Finch, C. E. AU - Klein, W. L. PY - 2001 DA - 2001// TI - Vaccination with soluble abeta oligomers generates toxicity-neutralizing antibodies JO - J Neurochem VL - 79 UR - https://doi.org/10.1046/j.1471-4159.2001.00592.x DO - 10.1046/j.1471-4159.2001.00592.x ID - Lambert2001 ER - TY - JOUR AU - Kayed, R. AU - Head, E. AU - Thompson, J. L. AU - McIntire, T. M. AU - Milton, S. C. AU - Cotman, C. W. AU - Glabe, C. G. PY - 2003 DA - 2003// TI - Common structure of soluble amyloid oligomers implies common mechanism of pathogenesis JO - Science VL - 300 UR - https://doi.org/10.1126/science.1079469 DO - 10.1126/science.1079469 ID - Kayed2003 ER - TY - JOUR AU - Lacor, P. N. AU - Buniel, M. C. AU - Chang, L. AU - Fernandez, S. J. AU - Gong, Y. AU - Viola, K. L. AU - Lambert, M. P. AU - Velasco, P. T. AU - Bigio, E. H. AU - Finch, C. E. AU - Krafft, G. A. AU - Klein, W. L. PY - 2004 DA - 2004// TI - Synaptic targeting by alzheimer's-related amyloid beta oligomers JO - J Neurosci VL - 24 UR - https://doi.org/10.1523/JNEUROSCI.3432-04.2004 DO - 10.1523/JNEUROSCI.3432-04.2004 ID - Lacor2004 ER - TY - JOUR AU - Kokubo, H. AU - Kayed, R. AU - Glabe, C. G. AU - Yamaguchi, H. PY - 2005 DA - 2005// TI - Soluble abeta oligomers ultrastructurally localize to cell processes and might be related to synaptic dysfunction in alzheimer's disease brain JO - Brain Res VL - 1031 UR - https://doi.org/10.1016/j.brainres.2004.10.041 DO - 10.1016/j.brainres.2004.10.041 ID - Kokubo2005 ER - TY - JOUR AU - Lee, E. B. AU - Leng, L. Z. AU - Zhang, B. AU - Kwong, L. AU - Trojanowski, J. Q. AU - Abel, T. AU - Lee, V. M. PY - 2006 DA - 2006// TI - Targeting amyloid-beta peptide (abeta) oligomers by passive immunization with a conformation-selective monoclonal antibody improves learning and memory in abeta precursor protein (app) transgenic mice JO - J Biol Chem VL - 281 UR - https://doi.org/10.1074/jbc.M511018200 DO - 10.1074/jbc.M511018200 ID - Lee2006 ER - TY - JOUR AU - Bateman, D. A. AU - Chakrabartty, A. PY - 2004 DA - 2004// TI - Interactions of alzheimer amyloid peptides with cultured cells and brain tissue, and their biological consequences JO - Biopolymers VL - 76 UR - https://doi.org/10.1002/bip.10561 DO - 10.1002/bip.10561 ID - Bateman2004 ER - TY - JOUR AU - Holscher, C. PY - 2005 DA - 2005// TI - Development of beta-amyloid-induced neurodegeneration in alzheimer's disease and novel neuroprotective strategies JO - Rev Neurosci VL - 16 UR - https://doi.org/10.1515/REVNEURO.2005.16.3.181 DO - 10.1515/REVNEURO.2005.16.3.181 ID - Holscher2005 ER - TY - JOUR AU - Yan, S. D. AU - Chen, X. AU - Fu, J. AU - Chen, M. AU - Zhu, H. AU - Roher, A. AU - Slattery, T. AU - Zhao, L. AU - Nagashima, M. AU - Morser, J. AU - Migheli, A. AU - Nawroth, P. AU - Stern, D. AU - Schmidt, A. M. PY - 1996 DA - 1996// TI - Rage and amyloid-beta peptide neurotoxicity in alzheimer's disease JO - Nature VL - 382 UR - https://doi.org/10.1038/382685a0 DO - 10.1038/382685a0 ID - Yan1996 ER - TY - JOUR AU - Kajkowski, E. M. AU - Lo, C. F. AU - Ning, X. AU - Walker, S. AU - Sofia, H. J. AU - Wang, W. AU - Edris, W. AU - Chanda, P. AU - Wagner, E. AU - Vile, S. AU - Ryan, K. AU - McHendry-Rinde, B. AU - Smith, S. C. AU - Wood, A. AU - Rhodes, K. J. AU - Kennedy, J. D. AU - Bard, J. AU - Jacobsen, J. S. AU - Ozenberger, B. A. PY - 2001 DA - 2001// TI - Beta -amyloid peptide-induced apoptosis regulated by a novel protein containing a g protein activation module JO - J Biol Chem VL - 276 UR - https://doi.org/10.1074/jbc.M011161200 DO - 10.1074/jbc.M011161200 ID - Kajkowski2001 ER - TY - JOUR AU - Nagele, R. G. AU - D'Andrea, M. R. AU - Anderson, W. J. AU - Wang, H. PY - 2002 DA - 2002// TI - Intracellular accumulation of beta-amyloid(1–42) in neurons is facilitated by the alpha 7 nicotinic acetylcholine receptor in alzheimer's disease JO - Neuroscience VL - 110 UR - https://doi.org/10.1016/S0306-4522(01)00460-2 DO - 10.1016/S0306-4522(01)00460-2 ID - Nagele2002 ER - TY - JOUR AU - Bi, X. AU - Gall, C. M. AU - Zhou, J. AU - Lynch, G. PY - 2002 DA - 2002// TI - Uptake and pathogenic effects of amyloid beta peptide 1–42 are enhanced by integrin antagonists and blocked by nmda receptor antagonists JO - Neuroscience VL - 112 UR - https://doi.org/10.1016/S0306-4522(02)00132-X DO - 10.1016/S0306-4522(02)00132-X ID - Bi2002 ER -