Muskelin localization at the subcellular level. Cultured hippocampal neurons were counterstained for muskelin (red) and individual markers (green). Muskelin localizes to the neuronal nucleus (arrowhead, yellow) and displays a punctate distribution in the cell soma (arrows) and in MAP2-positive dendrites (green) as well as in NF-200-positive or tau-positive axons (green). Muskelin immunoreactivity is often found at the margins of neurites (crossed arrows in magnified images below), suggesting surface membrane association. Overlay of green and red fluorescent signals are represented in yellow. Scale bars: 15 μm (top), 7 μm (bottom).