Skip to main content
Figure 4 | BMC Neuroscience

Figure 4

From: Intracerebroventricular antisense knockdown of Gαi2 results in ciliary stasis and ventricular dilatation in the rat

Figure 4

Irreversible ventricular dilatation after 2-day AS-ODN infusion, imaged by high resolution MRI in vivo. Left: the status of ventricular system of AS-ODN treated rats on days 0, 2, 4, 7, 11. The brain is shown from rostral side, i.e. the targeted right lateral ventricle is on the left. The level of coronal MRI images correspond to ~Bregma -1.0. Right: ventricular volumes (μl) and wall surface areas (mm2) calculated from consecutive MRI images using the Cavalieri principle. Data represent mean ± SEM (n = 4–5 animals in each time point). ***, p < 0.001 significantly different from the contralateral ventricle, one-way ANOVA with Tukey's Multiple Comparison test.

Back to article page