Profile of WT and CRFR1-/- dams and pups. Neither pup number (A) nor dam weight (B) differed between genotype. In contrast, mean pup weight on postpartum Day 6 was significantly higher in WT relative to CRFR1-/- mice (C). Bars represent means ± SE. White bars indicate WT mice and black bars indicate CRFR1-/- mice. *** = p < 0.001; one-way ANOVA.