AVPV neurons containing estrogen receptor-beta in adult male rats are influenced by soy isoflavones

BMC Neuroscience

Table 1 The incidence of apoptosis in the AVPV of adult male Long-Evans rats^a

Group	Total Cell Number	Apoptotic Cell Number	Incidence of Apoptosis^b
Phyto-free	126	3	2.4
	125	1	0.8
	113	6	5.3
	133	8	6.0
	120	4	3.3
	*123.4 ± 3.3*	*4.4 ± 1.2^*	*3.6 ± 1.0^*
Phyto-600	111	32	28.8
	112	34	30.1
	108	41	38.0
	124	40	32.3
	125	45	36.0
	*116.0 ± 3.5*	*38.4 ± 2.4*	*33.1 ± 1.7*

^a The rats were exposed to either a soy isoflavone-free diet (Phyto-free) or a soy isoflavone-rich diet (Phyto-600) from conception until 150 days of age (n = 5 per diet treatment group).
^b Incidence of apoptosis was expressed as the percentage of apoptotic cell number over total cell number in AVPV.
^ Significantly greater apoptotic cell number or incidence of apoptosis in the Phyto-600 AVPV compared to the Phyto-free group (p < 0.05; two sample student t-test).

ISSN: 1471-2202