Figure 2From: Survival of adult neurons lacking cholesterol synthesis in vivoCerebella from mutant and control animals look indistinguishable at the age of two and six months. (A) Normal lobulation pattern. Sagittal paraffin sections stained with hematoxylin/eosin, scale bar = 1 mm. (B) Bergmann glia are normal and no astrogliosis is evident. GFAP stained paraffin sections (lobule 8); scale bar = 50 μm. (C) Granule cell dendrites are normally developed. Golgi impregnated sections showing individual granule cells; scale bar = 20 μm. (D) Purkinje cell spines are normal; single confocal planes of Purkinje cell dendrites stained for calbindin, scale bar = 5 μm.Back to article page