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Table 1 Number and morphology of cortical layer V microglia after sham-operation or LPS application

From: Effects of lipopolysaccharide-induced inflammation on expression of growth-associated genes by corticospinal neurons

  

Sham-operated

LPS-treated

  

Ramified microglia

Activated microglia

Ramified microglia

Activated microglia

3 days after LPS

Mean number

69

0.3

15.3

162

 

% of total

99.5

0.5

8.6

91.4

14 days after LPS

Mean number

75.3

0.3

77

2.3

 

% of total

99.6

0.4

97.1

2.9

1 month after LPS

Mean number

67

0

72

0

 

% of total

100

0

100

0

  1. Note: All microglia within an area of 400 μm × 340 μm (136,000 μm2) defined by a counting frame superimposed over a digitised image of layer V were counted and identified as either ramified (quiescent) or activated. Numbers represent means of 3 counts; % indicates relative proportions of ramified and activated microglia.