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Figure 5 | BMC Neuroscience

Figure 5

From: Estrogen protects neuronal cells from amyloid beta-induced apoptosis via regulation of mitochondrial proteins and function

Figure 5

17β-estradiol prevents Amyloid beta1–42-induced Bax translocation. Primary hippocampal neurons pretreated with E2 (10 ng/mL; 48 hr) or vehicle control were exposed to Aβ1–42 for 24 hr and mitochondrial fractions were assessed for Bax expression by (A) Western blot analysis and (B) immunocytochemistry. The order of bands was switched to maintain a consistent treatment order across all figures for presentation purposes only. All quantitation and analysis was performed unmodified images. (* = p < 0.05 as compared to control; ** = p < 0.01 as compared to control; + = p < 0.05 as compared to Aβ1–42 alone; n = 4).

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