TY - JOUR AU - Hakak, Y. AU - Walker, J. R. AU - Li, C. AU - Wong, W. H. AU - Davis, K. L. AU - Buxbaum, J. D. AU - Haroutunian, V. AU - Fienberg, A. A. PY - 2001 DA - 2001// TI - Genome-wide expression analysis reveals dysregulation of myelination-related genes in chronic schizophrenia JO - Proc Natl Acad Sci U S A VL - 98 UR - https://doi.org/10.1073/pnas.081071198 DO - 10.1073/pnas.081071198 ID - Hakak2001 ER - TY - JOUR AU - Hof, P. R. AU - Haroutunian, V. AU - Friedrich, V. L. J. AU - Byne, W. AU - Buitron, C. AU - Perl, D. P. AU - Davis, K. L. PY - 2003 DA - 2003// TI - Loss and altered spatial distribution of oligodendrocytes in the superior frontal gyrus in schizophrenia JO - Biol Psychiatry VL - 53 UR - https://doi.org/10.1016/S0006-3223(03)00237-3 DO - 10.1016/S0006-3223(03)00237-3 ID - Hof2003 ER - TY - JOUR AU - Davis, K. L. AU - Stewart, D. G. AU - Friedman, J. I. AU - Buchsbaum, M. AU - Harvey, P. D. AU - Hof, P. R. AU - Buxbaum, J. AU - Haroutunian, V. PY - 2003 DA - 2003// TI - White matter changes in schizophrenia: evidence for myelin-related dysfunction JO - Arch Gen Psychiatry VL - 60 UR - https://doi.org/10.1001/archpsyc.60.5.443 DO - 10.1001/archpsyc.60.5.443 ID - Davis2003 ER - TY - JOUR AU - Tkachev, D. AU - Mimmack, M. L. AU - Ryan, M. M. AU - Wayland, M. AU - Freeman, T. AU - Jones, P. B. AU - Starkey, M. AU - Webster, M. J. AU - Yolken, R. H. AU - Bahn, S. PY - 2003 DA - 2003// TI - Oligodendrocyte dysfunction in schizophrenia and bipolar disorder JO - Lancet VL - 362 UR - https://doi.org/10.1016/S0140-6736(03)14289-4 DO - 10.1016/S0140-6736(03)14289-4 ID - Tkachev2003 ER - TY - JOUR AU - Uranova, N. AU - Orlovskaya, D. AU - Vikhreva, O. AU - Zimina, I. AU - Kolomeets, N. AU - Vostrikov, V. AU - Rachmanova, V. PY - 2001 DA - 2001// TI - Electron microscopy of oligodendroglia in severe mental illness JO - Brain Res Bull VL - 55 UR - https://doi.org/10.1016/S0361-9230(01)00528-7 DO - 10.1016/S0361-9230(01)00528-7 ID - Uranova2001 ER - TY - JOUR AU - Dietschy, J. M. AU - Turley, S. D. PY - 2004 DA - 2004// TI - Thematic review series: brain Lipids. Cholesterol metabolism in the central nervous system during early development and in the mature animal JO - J Lipid Res VL - 45 UR - https://doi.org/10.1194/jlr.R400004-JLR200 DO - 10.1194/jlr.R400004-JLR200 ID - Dietschy2004 ER - TY - JOUR AU - Mauch, D. H. AU - Nagler, K. AU - Schumacher, S. AU - Goritz, C. AU - Muller, E. C. AU - Otto, A. AU - Pfrieger, F. W. PY - 2001 DA - 2001// TI - CNS synaptogenesis promoted by glia-derived cholesterol JO - Science VL - 294 UR - https://doi.org/10.1126/science.294.5545.1354 DO - 10.1126/science.294.5545.1354 ID - Mauch2001 ER - TY - JOUR AU - Remington, G. PY - 2003 DA - 2003// TI - Understanding antipsychotic "atypicality": a clinical and pharmacological moving target JO - J Psychiatry Neurosci VL - 28 ID - Remington2003 ER - TY - JOUR AU - Davis, J. M. AU - Chen, N. AU - Glick, I. D. PY - 2003 DA - 2003// TI - A meta-analysis of the efficacy of second-generation antipsychotics JO - Arch Gen Psychiatry VL - 60 UR - https://doi.org/10.1001/archpsyc.60.6.553 DO - 10.1001/archpsyc.60.6.553 ID - Davis2003 ER - TY - JOUR AU - Remington, G. AU - Kapur, S. PY - 2000 DA - 2000// TI - Atypical antipsychotics: are some more atypical than others? JO - Psychopharmacology (Berl) VL - 148 UR - https://doi.org/10.1007/s002130050017 DO - 10.1007/s002130050017 ID - Remington2000 ER - TY - JOUR AU - Allison, D. B. AU - Mentore, J. L. AU - Heo, M. AU - Chandler, L. P. AU - Cappelleri, J. C. AU - Infante, M. C. AU - Weiden, P. J. PY - 1999 DA - 1999// TI - Antipsychotic-induced weight gain: a comprehensive research synthesis JO - Am J Psychiatry VL - 156 ID - Allison1999 ER - TY - JOUR AU - Ferno, J. AU - Raeder, M. B. AU - Vik-Mo, A. O. AU - Skrede, S. AU - Glambek, M. AU - Tronstad, K. J. AU - Breilid, H. AU - Lovlie, R. AU - Berge, R. K. AU - Stansberg, C. AU - Steen, V. M. PY - 2005 DA - 2005// TI - Antipsychotic drugs activate SREBP-regulated expression of lipid biosynthetic genes in cultured human glioma cells: a novel mechanism of action? JO - Pharmacogenomics J VL - 5 UR - https://doi.org/10.1038/sj.tpj.6500323 DO - 10.1038/sj.tpj.6500323 ID - Ferno2005 ER - TY - JOUR AU - Horton, J. D. AU - Goldstein, J. L. AU - Brown, M. S. PY - 2002 DA - 2002// TI - SREBPs: activators of the complete program of cholesterol and fatty acid synthesis in the liver JO - J Clin Invest VL - 109 UR - https://doi.org/10.1172/JCI0215593 DO - 10.1172/JCI0215593 ID - Horton2002 ER - TY - JOUR AU - Horton, J. D. AU - Shah, N. A. AU - Warrington, J. A. AU - Anderson, N. N. AU - Park, S. W. AU - Brown, M. S. AU - Goldstein, J. L. PY - 2003 DA - 2003// TI - Combined analysis of oligonucleotide microarray data from transgenic and knockout mice identifies direct SREBP target genes JO - Proc Natl Acad Sci U S A VL - 100 UR - https://doi.org/10.1073/pnas.1534923100 DO - 10.1073/pnas.1534923100 ID - Horton2003 ER - TY - JOUR AU - Shimano, H. AU - Horton, J. D. AU - Shimomura, I. AU - Hammer, R. E. AU - Brown, M. S. AU - Goldstein, J. L. PY - 1997 DA - 1997// TI - Isoform 1c of sterol regulatory element binding protein is less active than isoform 1a in livers of transgenic mice and in cultured cells JO - J Clin Invest VL - 99 UR - https://doi.org/10.1172/JCI119248 DO - 10.1172/JCI119248 ID - Shimano1997 ER - TY - JOUR AU - Shimomura, I. AU - Shimano, H. AU - Horton, J. D. AU - Goldstein, J. L. AU - Brown, M. S. PY - 1997 DA - 1997// TI - Differential expression of exons 1a and 1c in mRNAs for sterol regulatory element binding protein-1 in human and mouse organs and cultured cells JO - J Clin Invest VL - 99 UR - https://doi.org/10.1172/JCI119247 DO - 10.1172/JCI119247 ID - Shimomura1997 ER - TY - JOUR AU - Shimano, H. AU - Horton, J. D. AU - Hammer, R. E. AU - Shimomura, I. AU - Brown, M. S. AU - Goldstein, J. L. PY - 1996 DA - 1996// TI - Overproduction of cholesterol and fatty acids causes massive liver enlargement in transgenic mice expressing truncated SREBP-1a JO - J Clin Invest VL - 98 UR - https://doi.org/10.1172/JCI118951 DO - 10.1172/JCI118951 ID - Shimano1996 ER - TY - JOUR AU - Horton, J. D. AU - Bashmakov, Y. AU - Shimomura, I. AU - Shimano, H. PY - 1998 DA - 1998// TI - Regulation of sterol regulatory element binding proteins in livers of fasted and refed mice JO - Proc Natl Acad Sci U S A VL - 95 UR - https://doi.org/10.1073/pnas.95.11.5987 DO - 10.1073/pnas.95.11.5987 ID - Horton1998 ER - TY - JOUR AU - Janowski, B. A. AU - Shan, B. AU - Russell, D. W. PY - 2001 DA - 2001// TI - The hypocholesterolemic agent LY295427 reverses suppression of sterol regulatory element-binding protein processing mediated by oxysterols JO - J Biol Chem VL - 276 UR - https://doi.org/10.1074/jbc.M108348200 DO - 10.1074/jbc.M108348200 ID - Janowski2001 ER - TY - JOUR AU - Lange, Y. AU - Ye, J. AU - Rigney, M. AU - Steck, T. L. PY - 1999 DA - 1999// TI - Regulation of endoplasmic reticulum cholesterol by plasma membrane cholesterol JO - J Lipid Res VL - 40 ID - Lange1999 ER - TY - JOUR AU - Kroeze, W. K. AU - Hufeisen, S. J. AU - Popadak, B. A. AU - Renock, S. M. AU - Steinberg, S. AU - Ernsberger, P. AU - Jayathilake, K. AU - Meltzer, H. Y. AU - Roth, B. L. PY - 2003 DA - 2003// TI - H1-histamine receptor affinity predicts short-term weight gain for typical and atypical antipsychotic drugs JO - Neuropsychopharmacology VL - 28 UR - https://doi.org/10.1038/sj.npp.1300027 DO - 10.1038/sj.npp.1300027 ID - Kroeze2003 ER - TY - JOUR AU - Miyamoto, S. AU - Duncan, G. E. AU - Marx, C. E. AU - Lieberman, J. A. PY - 2005 DA - 2005// TI - Treatments for schizophrenia: a critical review of pharmacology and mechanisms of action of antipsychotic drugs JO - Mol Psychiatry VL - 10 UR - https://doi.org/10.1038/sj.mp.4001556 DO - 10.1038/sj.mp.4001556 ID - Miyamoto2005 ER - TY - JOUR AU - Raeder, M. B. AU - Ferno, J. AU - Glambek, M. AU - Stansberg, C. AU - Steen, V. M. PY - 2006 DA - 2006// TI - Antidepressant drugs activate SREBP and up-regulate cholesterol and fatty acid biosynthesis in human glial cells JO - Neurosci Lett VL - 395 UR - https://doi.org/10.1016/j.neulet.2005.10.096 DO - 10.1016/j.neulet.2005.10.096 ID - Raeder2006 ER - TY - JOUR AU - Lange, Y. AU - Steck, T. L. PY - 1994 DA - 1994// TI - Cholesterol homeostasis. Modulation by amphiphiles JO - J Biol Chem VL - 269 ID - Lange1994 ER - TY - JOUR AU - Nohturfft, A. AU - DeBose-Boyd, R. A. AU - Scheek, S. AU - Goldstein, J. L. AU - Brown, M. S. PY - 1999 DA - 1999// TI - Sterols regulate cycling of SREBP cleavage-activating protein (SCAP) between endoplasmic reticulum and Golgi JO - Proc Natl Acad Sci U S A VL - 96 UR - https://doi.org/10.1073/pnas.96.20.11235 DO - 10.1073/pnas.96.20.11235 ID - Nohturfft1999 ER - TY - JOUR AU - Adams, C. M. AU - Reitz, J. AU - De Brabander, J. K. AU - Feramisco, J. D. AU - Li, L. AU - Brown, M. S. AU - Goldstein, J. L. PY - 2004 DA - 2004// TI - Cholesterol and 25-hydroxycholesterol inhibit activation of SREBPs by different mechanisms, both involving SCAP and Insigs JO - J Biol Chem VL - 279 UR - https://doi.org/10.1074/jbc.M410302200 DO - 10.1074/jbc.M410302200 ID - Adams2004 ER - TY - JOUR AU - Adams, C. M. AU - Goldstein, J. L. AU - Brown, M. S. PY - 2003 DA - 2003// TI - Cholesterol-induced conformational change in SCAP enhanced by Insig proteins and mimicked by cationic amphiphiles JO - Proc Natl Acad Sci U S A VL - 100 UR - https://doi.org/10.1073/pnas.1534833100 DO - 10.1073/pnas.1534833100 ID - Adams2003 ER - TY - JOUR AU - Saher, G. AU - Brugger, B. AU - Lappe-Siefke, C. AU - Mobius, W. AU - Tozawa, R. AU - Wehr, M. C. AU - Wieland, F. AU - Ishibashi, S. AU - Nave, K. A. PY - 2005 DA - 2005// TI - High cholesterol level is essential for myelin membrane growth JO - Nat Neurosci VL - 8 ID - Saher2005 ER - TY - JOUR AU - Ness, G. C. PY - 1994 DA - 1994// TI - Developmental regulation of the expression of genes encoding proteins involved in cholesterol homeostasis JO - Am J Med Genet VL - 50 UR - https://doi.org/10.1002/ajmg.1320500411 DO - 10.1002/ajmg.1320500411 ID - Ness1994 ER - TY - JOUR AU - Glantz, L. A. AU - Lewis, D. A. PY - 2000 DA - 2000// TI - Decreased dendritic spine density on prefrontal cortical pyramidal neurons in schizophrenia JO - Arch Gen Psychiatry VL - 57 UR - https://doi.org/10.1001/archpsyc.57.1.65 DO - 10.1001/archpsyc.57.1.65 ID - Glantz2000 ER - TY - JOUR AU - Honer, W. G. AU - Falkai, P. AU - Chen, C. AU - Arango, V. AU - Mann, J. J. AU - Dwork, A. J. PY - 1999 DA - 1999// TI - Synaptic and plasticity-associated proteins in anterior frontal cortex in severe mental illness JO - Neuroscience VL - 91 UR - https://doi.org/10.1016/S0306-4522(98)00679-4 DO - 10.1016/S0306-4522(98)00679-4 ID - Honer1999 ER - TY - JOUR AU - Lewis, D. A. PY - 1997 DA - 1997// TI - Development of the prefrontal cortex during adolescence: insights into vulnerable neural circuits in schizophrenia JO - Neuropsychopharmacology VL - 16 UR - https://doi.org/10.1016/S0893-133X(96)00277-1 DO - 10.1016/S0893-133X(96)00277-1 ID - Lewis1997 ER - TY - JOUR AU - Mirnics, K. AU - Middleton, F. A. AU - Lewis, D. A. AU - Levitt, P. PY - 2001 DA - 2001// TI - Analysis of complex brain disorders with gene expression microarrays: schizophrenia as a disease of the synapse JO - Trends Neurosci VL - 24 UR - https://doi.org/10.1016/S0166-2236(00)01862-2 DO - 10.1016/S0166-2236(00)01862-2 ID - Mirnics2001 ER - TY - JOUR AU - Goritz, C. AU - Mauch, D. H. AU - Pfrieger, F. W. PY - 2005 DA - 2005// TI - Multiple mechanisms mediate cholesterol-induced synaptogenesis in a CNS neuron JO - Mol Cell Neurosci VL - 29 UR - https://doi.org/10.1016/j.mcn.2005.02.006 DO - 10.1016/j.mcn.2005.02.006 ID - Goritz2005 ER - TY - JOUR AU - Pfrieger, F. W. PY - 2003 DA - 2003// TI - Outsourcing in the brain: do neurons depend on cholesterol delivery by astrocytes? JO - Bioessays VL - 25 UR - https://doi.org/10.1002/bies.10195 DO - 10.1002/bies.10195 ID - Pfrieger2003 ER - TY - JOUR AU - Baumann, P. AU - Hiemke, C. AU - Ulrich, S. AU - Eckermann, G. AU - Gaertner, I. AU - Gerlach, M. AU - Kuss, H. J. AU - Laux, G. AU - Muller-Oerlinghausen, B. AU - Rao, M. L. AU - Riederer, P. AU - Zernig, G. PY - 2004 DA - 2004// TI - The AGNP-TDM expert group consensus guidelines: therapeutic drug monitoring in psychiatry JO - Pharmacopsychiatry VL - 37 UR - https://doi.org/10.1055/s-2004-832687 DO - 10.1055/s-2004-832687 ID - Baumann2004 ER - TY - JOUR AU - Kornhuber, J. AU - Schultz, A. AU - Wiltfang, J. AU - Meineke, I. AU - Gleiter, C. H. AU - Zochling, R. AU - Boissl, K. W. AU - Leblhuber, F. AU - Riederer, P. PY - 1999 DA - 1999// TI - Persistence of haloperidol in human brain tissue JO - Am J Psychiatry VL - 156 UR - https://doi.org/10.1176/ajp.156.6.885 DO - 10.1176/ajp.156.6.885 ID - Kornhuber1999 ER - TY - JOUR AU - Weigmann, H. AU - Hartter, S. AU - Fischer, V. AU - Dahmen, N. AU - Hiemke, C. PY - 1999 DA - 1999// TI - Distribution of clozapine and desmethylclozapine between blood and brain in rats JO - Eur Neuropsychopharmacol VL - 9 UR - https://doi.org/10.1016/S0924-977X(98)00036-4 DO - 10.1016/S0924-977X(98)00036-4 ID - Weigmann1999 ER - TY - JOUR AU - Buchanan, R. W. AU - Breier, A. AU - Kirkpatrick, B. AU - Ball, P. AU - Carpenter, W. T. J. PY - 1998 DA - 1998// TI - Positive and negative symptom response to clozapine in schizophrenic patients with and without the deficit syndrome JO - Am J Psychiatry VL - 155 UR - https://doi.org/10.1176/ajp.155.8.1049 DO - 10.1176/ajp.155.8.1049 ID - Buchanan1998 ER - TY - JOUR AU - Freedman, R. PY - 2003 DA - 2003// TI - Schizophrenia JO - N Engl J Med VL - 349 UR - https://doi.org/10.1056/NEJMra035458 DO - 10.1056/NEJMra035458 ID - Freedman2003 ER - TY - JOUR AU - Akslen, L. A. AU - Andersen, K. J. AU - Bjerkvig, R. PY - 1988 DA - 1988// TI - Characteristics of human and rat glioma cells grown in a defined medium JO - Anticancer Res VL - 8 ID - Akslen1988 ER - TY - JOUR AU - Winer, J. AU - Jung, C. K. AU - Shackel, I. AU - Williams, P. M. PY - 1999 DA - 1999// TI - Development and validation of real-time quantitative reverse transcriptase-polymerase chain reaction for monitoring gene expression in cardiac myocytes in vitro JO - Anal Biochem VL - 270 UR - https://doi.org/10.1006/abio.1999.4085 DO - 10.1006/abio.1999.4085 ID - Winer1999 ER -