Figure 3

Inhibition of prefrontal protein synthesis following remote recall of a two-day trace fear conditioning paradigm does not disrupt memory. A, Scheme illustrating the chronology of training sessions on two consecutive days (eight CS-US per day), reactivation at 30 days following training, intra-mPFC infusion, and retention testing in a novel context (two days following the infusions). B, Graph of the mean ± SEM percent freezing prior to CS presentation, during the CS, and during the trace period of the reactivation trial for intra-mPFC anisomycin- and vehicle-infused groups. C, Graph of the mean ± SEM percent freezing during the pre-CS, CS and trace periods for the retention testing trials, expressed as an average of four trials.