Evolutionary conservation of the GRIK2 3'UTR region. Plots comparing chimpanzee, dog, rat, mouse, chicken and frog orthologue sequences to the conserved 3'UTR region of human GRIK2 were generated using mVISTA [34-36]. For the human sequence, we chose chr6: 102623080–102624690, comprising 1610 bp sequence downstream from the stop codon, based upon the report of a polyadenylation signal at 1547 bp after the stop codon . The relative location of the polymorphic TAA repeat within the human sequence is shown between vertical lines (from 787 to 828bp). Plots show % identity over a 100 bp window (vertical axis) of chimpanzee (chr5 (Nov 2003): 104613747-104615339), dog (chr12 (July 2004): 62913564-62915139), rat (chr20 (June 2003): 53258651-53260220), mouse (chr10 (May 2004): 49099305-49100874), chicken (chr3 (Feb 2004): 68531473-68532948), and frog (Xenopus tropicalis) (Scaffold-599 (Oct 2004): 27668-29079), respectively, relative to the human sequence (horizontal axis) .