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Figure 9 | BMC Neuroscience

Figure 9

From: Insulin-like growth factor-1 (IGF-1) induces the activation/phosphorylation of Akt kinase and cAMP response element-binding protein (CREB) by activating different signaling pathways in PC12 cells

Figure 9

EGF, FGF, FBS, PMA and the calcium ionophore-A23187 stimulated CREB phosphorylation in PC12 cells. PC12 cells were treated with 10 nM IGF-1, 4 nM EGF, 4 nM FGF, 10% FBS, 200 nM PMA and 10 μM A23187 and the phosphorylation of CREB was determined as described in Methods. All these agents stimulated CREB phosphorylation in PC12 cells. Blots represent prototypical examples of experiments replicated at least 3 times.

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BMC Neuroscience

ISSN: 1471-2202

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