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Figure 1 | BMC Neuroscience

Figure 1

From: Homozygous mutation of focal adhesion kinase in embryonic stem cell derived neurons: normal electrophysiological and morphological properties in vitro

Figure 1

FAK locus targeting. Simplified diagram of FAK locus targeting strategy. The top of the panel shows the targeted allele containing 3 loxP sites. Below is shown one of the deletion products following cre recombinase expression, with ATP binding loops deleted. This was used in the present study to generate homozygous FAK null ES cells after a second round of targeting and deletion, depicted schematically in the lower panel. For further details see additional file [1]1and [9].

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BMC Neuroscience

ISSN: 1471-2202

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