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Table 1 Parameters of the model. Values used in the fits illustrated in Figs 2 and 3 are compared with the generic values for macaque reported in [3].

From: The photocurrent response of human cones is fast and monophasic

Parameter

Description

Generic macaque cone [3]

Human cone (Fig. 2)

Ground squirrel (Fig. 3)

Units

Ï„R

Time constant of R* inactivation

3.4

3.4

3.0

ms

Ï„E

Time constant of E* inactivation

8.7

9.6

13

ms

Ï„D

Time constant of cGMP hydrolysis in darkness

360

360

60

ms

k β

Coupling gain from light intensity to rate of hydrolysis of cGMP

1.6·10-4

10-4

 

(ms)-1 td-1

    

2.1·10-7

(ms)-1 (isom/s)-1

n X

Apparent Hill coefficient of CNG channel activation

1

1

1.7

-

Ï„Ca

Time constant of Ca2+ extrusion

3

3

4.8

ms

n cyc

Hill coefficient of GC activation

4

4

3.2

-

a cyc

Scaling constant of GC activation

9·10-2

9·10-2

3.7·10-2

-

Ï„m

Outer segment capacitive time constant

< 4

2.3

2.3

ms

t delay

Delay time

< 3

1.3

2.2

ms