Figure 9
From: An extremely rich repertoire of bursting patterns during the development of cortical cultures
Development of functional projections in cultures of different densities. Median distance of sites of non-synaptic responses to stimulated electrode (solid, dots) and 90th percentile of distance distribution (dashed, circle) in individual recordings from dense culture, small cultures, and sparse cultures (left to right). The diameter of the MEA (maximum electrode distance) is 1.72 mm. Projections likely continued to grow beyond this length, especially in the dense cultures, but our method is incapable of following that development. (Interpolation was performed with a window half-width of 1 day for the leftmost panel, and 2 days for the other two, to obtain a smooth curve for the smaller data sets.)