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Figure 4 | BMC Neuroscience

Figure 4

From: Signalling crosstalk in FGF2-mediated protection of endothelial cells from HIV-gp120

Figure 4

Effects of inhibitors on FGF2-stimulated ERK and GSK3β activity Immunocomplex kinase assays for (A) ERK and (B) GSK3β activity without FGF2 treatment, or after inhibition with PD98059, U0126, LY29004, Bisindolymaleimide I or Gö6983 followed by FGF2 treatment. (C) Inhibitor treatment alone. (D) Summary of changes in phosphorylation (P) versus changes in activity (Act) of ERK and GSK3β. Indicates an increase, indicates a decrease, – indicates no change. * = P < 0.05 by One-Way ANOVA with post-hoc Dunnett's when compared to control.

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