Table 1 Effects of MCEPH on Kv1.2 and Kv1.3 kinetics in Xenopus oocytes. Mean midpoints of activation and inactivation curves (V1/2) and mean half time values (t1/2) for Kv1.2 and Kv1.3 (±SD), when expressed separately and when coexpressed with MCEPH. n is the number of oocytes. The activation and inactivation curves were constructed from measurements based on the stimulation protocols in Fig. 5. Half time value (t1/2) was measured as time to half peak current at a 50 mV pulse step (±SD).
From: A truncated Kv1.1 protein in the brain of the megencephalymouse: expression and interaction
Steady-state activation | Steady-state inactivation | n | ||
|---|---|---|---|---|
V1/2 (mV) | t1/2 (ms) | V1/2 (mV) | ||
Kv1.2 | -24 ± 4 | 3 ± 1 | -17 ± 7 | 9 |
Kv1.2 + MCEPH | -22 ± 3 | 3 ± 1 | -18 ± 6 | 10 |
Kv1.3 | -25 ± 4 | 6 ± 3 | -29 ± 3 | 7 |
Kv1.3 + MCEPH | -31 ± 4 | 6 ± 3 | -34 ± 4 | 10 |