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Figure 9 | BMC Neuroscience

Figure 9

From: The neuroblast and angioblast chemotaxic factor SDF-1 (CXCL12) expression is briefly up regulated by reactive astrocytes in brain following neonatal hypoxic-ischemic injury

Figure 9

Astrocyte Expression of SDF-1. GFAP and SDF-1 dual labeling is demonstrated by confocal microscopy in P10 mice, three days post-HI. Panels A-C, from the striatum, show perivascular (arrowheads) astrocyte (GFAP – green) expression of SDF-1 (red). Panels D-F, from the hippocampus, show (arrowhead) similar co-labeling of GFAP (green) astrocyte cell bodies and processes for SDF-1 (red). Panels C and F show GFAP and SDF-1 co-labeling in merged orthogonal views of confocal z stacks. GFAP staining is shown in green and SDF-1 staining in Red. Panels A, B, D, and E are single z plane field images captured with a 63× objective. Scale bar equals 50 μm.

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