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Table 1 Human Tissue Donor Information

From: RLIP76, a non-ABC transporter, and drug resistance in epilepsy

ID

Age

Sex

Notes

AED failed

Use

1

0.8

M

EPi- Hemispherectomy

None

WB

2

0.3

M

Epi-Hemispherectomy

Ketogenic Diet

WB, AED transport studies

3

57

F

Temporal Lobe Epilepsy

PHE, CBZ,TPM

WB

4

33

F

Control (AVM)

None

WB

5

61

F

Temporal Lobe epilepsy

VAL,CBZ,TPB

WB, AED transport studies

6

30

M

Control Parasaggital Cist

None

WB, AED transport studies

7

0.9

F

Frontal/Parietal Epilepsy

VAL, PBT, TPM

WB

8

14

M

Temporal Lobe Epilepsy

CBZ, Keppra, PBT,TPM, VAL

WB

9

42

M

Temporal Lobe Epilepsy

VAL, PBT, primidone, tiagabine,

AED transport studies

10

27

F

Temporal Lobe Epilepsy

PHE,VAL,gabapentin,CBZ, TPM

AED transport studies

11

7

M

R. Lateral Parietal/Occipital/Temporal Lobes

PBT, PHE, TPM, CBZ, DZP, LMT

AED transport studies

12

14

M

Temporal Lobe Epilepsy

VAL,Keppra, CBZ, other

AED transport studies

13

31

F

Temporal Lobe Epilepsy

gabapentin, CBZ,VAL,PHE,PBT

AED transport studies

14

60

F

Temporal Lobe Epilepsy

PBT, MBL, TGL, DPT, VLM, MSL, FBT

In vitro cells AED

15

43

F

Focal Epi

N/A

In vitro cells AED

16

56

M

Focal Epi

PHE, PBT, CBZ, VAL, ETS

In vitro cells AED

17

43

F

Temporal Lobe Epilepsy

PHE, CBZ, VAL, GBP

mRNA analysis

18

40

F

Control (Aneurysm)

NONE

mRNA analysis

20

58

F

Focal Epi

PHE, PBT, VAL, PRM, FBT, GBP, TPM

mRNA analysis

21

35

M

Temporal Lobe Epilepsy

PHE, CBZ, VAL, PRM, VGB

mRNA analysis

22

28

M

Temporal Lobe Epilepsy

PHE, PBT, CBZ, VAL, TPM, CZP, GBP

mRNA analysis

23

38

M

Temporal Lobe Epilepsy

PHE, CBZ, VAL, FBM, GBP

mRNA analysis

24

39

M

Temporal Lobe Epilepsy

PHE, PBT, VAL, PRM, MSD

mRNA analysis

25

31

M

Temporal Lobe Epilepsy

PHE, PBT, VAL, TPM

mRNA analysis

26

23

M

Temporal Lobe Epilepsy

PHE, PBT, CBZ, VAL, GBP

mRNA analysis

27

45

F

Control (Aneurysm)

NONE

mRNA analysis

28

22

F

Control (Aneurysm)

NONE

mRNA analysis

36

7

M

Temporal Lobe Epilepsy

PHE, CBZ, VAL, GBP

ICC

37

28

F

Temporal Lobe Epilepsy

PHE, PBT, CBZ, VAL

ICC

38

7

M

Temporal Lobe Epilepsy

?

ICC

39

4

F

Frontal and Parietal Epilepsy

PHE, CBZ, VAL, PRM,

ICC

40

8

F

Temporal lobe epilepsy

CBZ, PHE, VAL

ICC

41

24

M

Control (AVM)

NONE

ICC

42

1

M

Frontal Epilepsy

CBZ, PHE, VAL

ICC

43

25

M

Temporal Lobe Epilepsy

Phe CBZ

ICC

44

1

M

Hemispherectomy

None

ICC

45

23

F

Contol (AVM)

None

ICC

46

23

M

Temporal lobe epilepsy

gabapentin, CBZ,VAL,PHE,

ICC

47

23

M

Control (AVM)

None

ICC

48

7

M

TSC

?

ICC

49

3

F

Epilepsy Right Hemi

?

ICC

50

  

Autopsy

 

ICC

51

  

Autopsy

 

ICC

52

  

Autopsy

 

ICC

53

  

Autopsy

 

ICC

54

  

Autopsy

 

ICC,WB

55

  

Autopsy

 

ICC,WB