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Figure 2 | BMC Neuroscience

Figure 2

From: Reduction of the hand representation in the ipsilateral primary motor cortex following unilateral section of the corticospinal tract at cervical level in monkeys

Figure 2

Experimental paradigm in Mks1-3. A cervical (left) sub-hemi-section at C7/C8 interrupted the main crossed corticospinal tract originating from the contralesional (right) hemisphere (RH) and the small, uncrossed, corticospinal tract, originating from the ipsilesional (left) hemisphere (LH). In order to assess the functional changes induced by the lesion in the ipsilesional hemisphere, electrode penetrations were performed in order to deliver intracortical microstimulations (ICMS) in the ipsilesional hemisphere. The effects of the ICMS were observed on the contralesional (right) side of the body, with emphasis on the contralesional hand, not affected by the lesion. In the present study, no effects were observed in the ipsilesional hand, affected by the lesion, for ICMS applied to the ipsilesional hemisphere. In other words, all ICMS effects reported in the present study are for the contralesional hand. MN = motoneuron

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