Infarct size, edema formation and hemoglobin excess differences between control and PMN-depleted animals. (A). Infarct size, as measured by TTC staining, indicated no differences between depletion and control groups. (B). Likewise, PMN depletion had no affect on the development of hemorrhagic transformation. (C) Edema determined as the difference in area between the ischemic and non-ischemic hemispheres was similar in neutrophil-depleted and control animals (n = 8 control, n = 10 PMN).