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Figure 10 | BMC Neuroscience

Figure 10

From: Synaptic and genomic responses to JNK and AP-1 signaling in Drosophila neurons

Figure 10

white transcript levels are induced when positive JNK pathway components are overexpressed in the fly nervous system. A) Quantitative comparisons of white transcript levels in adult head RNA from RU486 treated versus control samples. PCR primers designed to the 3' end of white (black), but not 5' primers (gray), show increased levels in response to AP-1 and hepact induction (N = 3). Wild-type flies exposed to hormone or flies overexpressing fbz do not show induction of white. X-axis indicates the UAS-transgene(s) induced. *Average treated difference significant at P < 0.05 (Student's t-test). B)in situ confirmation of increase in white transcript levels following hepact induction in the larval CNS.

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