Table 1 Lesion coordinates. Excitotoxic lesions of the entire hippocampus were made by injecting 0.09 M NMDA at the coordinates shown (see Methods). Along the anteroposterior (AP), mediolateral (ML), and dorsoventral (DV) axes, positive coordinates are in the anterior, left, and superior directions respectively. All coordinates are in mm. DV coordinates are measured from the dura above the injection site.
Region within hippocampus | Sites per hemisphere | AP | ML | DV | Volume injected per site | Duration of each infusion | Time allowed for diffusion after each infusion |
|---|---|---|---|---|---|---|---|
Dorsal | 2 | -2.8 | ± 1.6 | -3.3 | 0.4 μl | 4 min | 3 min |
|  |  | -4.2 | ± 2.6 | -3.0 | 0.4 μl | 4 min | 3 min |
Ventral | 4 | -4.8 | ± 4.8 | -6.0 | 0.2 μl | 2 min | 3 min |
|  |  | -5.3 | ± 4.6 | -4.2 | 0.2 μl | 2 min | 3 min |
|  |  | -5.3 | ± 4.6 | -6.0 | 0.2 μl | 2 min | 3 min |
|  |  | -5.8 | ± 4.6 | -4.2 | 0.2 μl | 2 min | 3 min |