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Figure 2 | BMC Neuroscience

Figure 2

From: Effects of prostaglandin E2 on the electrical properties of thermally classified neurons in the ventromedial preoptic area of the rat hypothalamus

Figure 2

The effects of temperature and PGE 2 on the activity of a VMPO temperature insensitive neuron and a VMPO warm sensitive neuron. The top panels show one second records of the action potential activity of a VMPO temperature insensitive neuron during all three experimental conditions (resting membrane potential = -43.94 mV). The firing rate significantly increased from a baseline of 5.11 ± 0.12 impulses·s-1 to 7.33 ± 0.13 impulses·s-1 during perfusion with 1 μM PGE2 (washout = 4.90 ± 0.14 impulses·s-1). The lower panels show one second records of the action potential activity of a VMPO warm sensitive neuron during all three experimental conditions (resting membrane potential = -51.62 mV). The firing rate significantly decreased from a baseline of 10.07 ± 0.13 impulses·s-1 to 8.40 ± 0.12 impulses·s-1 during perfusion with 1 μM PGE2 (washout = 10.20 ± 0.16 impulses·s-1).

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