From: The responses of Ht22 cells to oxidative stress induced by buthionine sulfoximine (BSO)
Protein/gene | Â | Normalized Intensity of control | Normalized Intensity of BSO sample | Ratio |
---|---|---|---|---|
mRNA increased | Â | Â | Â | Â |
heat shock cognate 71-kDa protein (HSC73; HSC70) | Y00054 | 1773 | 4780 | 2.70 |
eukaryotic peptide chain release factor subunit 1 (ERF1); TB3-1; C11 protein [rat homolog of human] | M75715 (human) | 208 | 519 | 2.50 |
thioredoxin peroxidase 2 (TDPX2); thioredoxin-dependent peroxide reductase 2; heme-binding 23-kDa protein (HBP23) | D30035 | 1710 | 3989 | 2.33 |
78-kDa glucose-regulated protein precursor (GRP78); immunoglobulin heavy chain binding protein (BIP); steroidogenesis-activator polypeptide; HSPA5 | M14050 | 66 | 154 | 2.33 |
60S ribosomal protein L6 (RPL6) | X87107 | 1932 | 4353 | 2.25 |
copper-zinc-containing superoxide dismutase 1 (Cu-Zn SOD1) | Y00404 | 1285 | 2813 | 2.19 |
proliferating cell nuclear antigen (PCNA); cyclin | Y00047 | 1463 | 3210 | 2.19 |
thymosin beta-10 (TMSB10; THYB10); PTMB10 | M17698 | 3545 | 7637 | 2.15 |
high mobility group protein 2 (HMG2) | D84418 | 957 | 1976 | 2.06 |
heat shock 90-kDa protein beta (HSP90-beta); HSP84; HSPCB | S45392 | 7737 | 15881 | 2.05 |
mRNA decreased | Â | Â | Â | Â |
DNA topoisomerase IIB (TOP2B) | D14046 | 4146 | 1502 | 0.36 |
osteopontin | M14656 | 3630 | 1535 | 0.42 |
contrapsin-like protease inhibitor related protein; SPI-3 serine protease inhibitor | D00753 | 13996 | 5961 | 0.43 |