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Figure 1 | BMC Neuroscience

Figure 1

From: The excitation cascade of Limulus ventral photoreceptors: guanylate cyclase as the link between InsP3-mediated Ca2+release and the opening of cGMP-gated channels

Figure 1

Guanosine 5'-tetraphosphate decreased and slowed the depolarization produced by 2.5 mM IBMX. (A) Bath application of 2.5 mM IBMX produced a characteristic depolarization of Limulus photoreceptors (control) that was diminished following intracellular pressure injection sufficient to inhibit the light response from a microelectrode containing 25 mM GtetP (GtetP). (B) Amplitudes of IBMX-induced depolarization in individual photoreceptors are matched before and after inhibition of the light response using GtetP. The thick line indicates the average decrease in depolarization (n = 10). (C) The maximum rising slopes of IBMX-induced depolarization in the same photoreceptors as in (B) are matched before and after inhibition of the light response using GtetP. The thick line indicates the average decrease in rising slope.

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