Figure 5
From: Bi-directional modulation of AMPA receptor unitary conductance by synaptic activity
NMDA receptor-dependence of DP. (A) Plot of amplitude vs. time from an experiment in which the DP induction protocol was delivered in the presence of D-AP5 (50 μM). Black bar represents LTP pairing, grey bar DP pairing protocol. (B) Changes in mean EPSC amplitude for normalised pooled data. Filled symbols: control (n = 5); open symbols: D-AP5 (n = 4). (C) Changes in potency for normalised pooled data (symbols as in B). For the analysis of LTP, amplitude and potency were measured for the 200 trials immediately preceding the DP pairing protocol.