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Figure 3 | BMC Neuroscience

Figure 3

From: Opioid modulation of GABA release in the rat inferior colliculus

Figure 3

Effect of subtype-specific opoid peptides on KCl-stimulted [3H]GABA release. DAMGO, DADLE and U69593 (1 μM) were perfused as described for morphine in Figure 1. Data represent averages ± SEM. Labels on the x-axis indicate concentration of drugs present during S2. Only the μ-opioid receptor specific neuropeptide DAMGO produced a statistically significant effect (p < 0.01, One way ANOVA) on KCl-stimulted [3H]GABA release as compared to the controls (a) where no opiate drug was used. The effect of DAMGO was antagonised by 10 μM naloxone which was perfused from one fraction before the perfusion of DAMGO (b).

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