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Table 2 Arecaidine but-2-ynyl ester tosylate does not induce pigment granule dispersion

From: Activation of muscarinic acetylcholine receptors elicits pigment granule dispersion in retinal pigment epithelium isolated from bluegill

Concentration Pigment Index± SEM n
0 nM 0.74 ± 0.01 4
1 nM 0.77 ± 0.03 4
10 nM 0.80 ± 0.02 4
100 nM 0.78 ± 0.02 4
1 μM 0.78 ± 0.01 4
  1. RPE was isolated from dark-adapted bluegill and, following incubation for 45 minutes in 10 μM forskolin, was incubated an additional 45 minutes in increasing concentrations of arecaidine but-2-ynyl ester tosylate or in a DMSO control. At the end of incubation in forskolin, RPE had a pigment index of 0.72 ± 0.02 (n = 4 fish); the 0.01% DMSO control had a pigment index of 0.69 ± 0.02 (n = 2 fish).