Figure 2

L1 immunoreactive neurons and transection of stria terminalis. a,a' and b,b'. Transection of the stria terminalis resulted in no accumulation of L1 on the proximal side of the nerve (a'; L1 knife cut), but caused accumulation in the case of substance P axons (b', SP knife cut, open arrowheads). L1 control; control side of the same section immunostained with antiCTL1 antibody. SP control; control side of the same section immunostained with antiSP antibody. c,c' and d,d' No change was found on L1 in the distal side of the lesion of the bundle (c'; L1 knife cut), though substance P immunoreactivity was clearly diminished (d'; SP knife cut, open arrowheads). e and f, Bright-field photomicrograph showing L1 neurons in the lateral posterior thalamic nucleus of the upper brainstem. a,a',b,b': Bar = 25 μm; c,c',d,d',e: Bar = 200 μm; f: Bar = 50 μm.