Figure 2
From: Syndecan-3 and syndecan-4 are enriched in Schwann cell perinodal processes
Localization of S3 in nodal regions of the PNS. (A-C) Sections through rat sciatic nerve at P30 were labeled with antibodies to S3 (green) and K+ channels (Kv1.1, A, red) or Na+ channels (Nav, B-C, red). Superposition of the two labels is shown (merge). Note that on sections perpendicular to nerve axis, S3 immunoreactivity is peripheral to Nav labeling. (D) Teased fiber from rat sciatic nerve stained for S3 (green) and Kv1.1 (red) showing that S3 immunoreactivity is on both sides of the node. B-D: confocal stacks. Scale bars: 10 μm (A, D), 1 μm (B, C).