| |
Basal
|
Histamine
|
P
|
---|
Mid-interbout
|
Cortex
|
0.271 ± 0.015
|
0.346 ± 0.021
|
0.0051
|
|
Caud
|
0.362 ± 0.015
|
0.439 ± 0.033
|
0.0367
|
|
Putamen
|
0.392 ± 0.023
|
0.458 ± 0.023
|
0.0462
|
|
GP
|
0.292 ± 0.016
|
0.420 ± 0.037
|
0.0020
|
|
SN
|
0.410 ± 0.021
|
0.597 ± 0.018
|
0.0001
|
End-interbout
|
Cortex
|
0.266 ± 0.012
|
0.327 ± 0.009
|
0.0002
|
|
Caud
|
0.316 ± 0.017
|
0.405 ± 0.021
|
0.0019
|
|
Putamen
|
0.277 ± 0.015
|
0.392 ± 0.020
|
0.0001
|
|
GP
|
0.271 ± 0.019
|
0.483 ± 0.022
|
0.0001
|
|
SN
|
0.402 ± 0.017
|
0.623 ± 0.023
|
0.0001
|
Hibernation
|
Cortex
|
0.162 ± 0.011
|
0.182 ± 0.010
|
0.1950
|
|
Caud
|
0.172 ± 0.016
|
0.177 ± 0.012
|
0.7777
|
|
Putamen
|
0.159 ± 0.012
|
0.168 ± 0.009
|
0.5356
|
|
GP
|
0.151 ± 0.012
|
0.231 ± 0.020
|
0.0030
|
|
SN
|
0.282 ± 0.012
|
0.362 ± 0.016
|
0.0004
|
Arousal
|
Cortex
|
0.185 ± 0.008
|
0.253 ± 0.010
|
0.0001
|
|
Caud
|
0.275 ± 0.005
|
0.312 ± 0.006
|
0.0001
|
|
Putamen
|
0.273 ± 0.007
|
0.296 ± 0.007
|
0.0175
|
|
GP
|
0.262 ± 0.009
|
0.317 ± 0.014
|
0.0001
|
|
SN
|
0.433 ± 0.035
|
0.721 ± 0.035
|
0.0001
|
- Basal and histamine-stimulated [35S]GTP-γ-S binding (IOD) in the ground squirrel basal ganglia across the hibernation bout. Mid-interbout n= 3, end-interbout n= 4, hibernation n= 4, arousal n= 3. P = Student's t-test. Caud = Caudate nucleus, GP = Globus pallidus, SN Substantia nigra pars reticulata.