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Table 1 Comparison of basal and histamine-stimulated [35S]GTP-γ-S binding.

From: Increased brain histamine H3 receptor expression during hibernation in golden-mantled ground squirrels

  

Basal

Histamine

P

Mid-interbout

Cortex

0.271 ± 0.015

0.346 ± 0.021

0.0051

 

Caud

0.362 ± 0.015

0.439 ± 0.033

0.0367

 

Putamen

0.392 ± 0.023

0.458 ± 0.023

0.0462

 

GP

0.292 ± 0.016

0.420 ± 0.037

0.0020

 

SN

0.410 ± 0.021

0.597 ± 0.018

0.0001

End-interbout

Cortex

0.266 ± 0.012

0.327 ± 0.009

0.0002

 

Caud

0.316 ± 0.017

0.405 ± 0.021

0.0019

 

Putamen

0.277 ± 0.015

0.392 ± 0.020

0.0001

 

GP

0.271 ± 0.019

0.483 ± 0.022

0.0001

 

SN

0.402 ± 0.017

0.623 ± 0.023

0.0001

Hibernation

Cortex

0.162 ± 0.011

0.182 ± 0.010

0.1950

 

Caud

0.172 ± 0.016

0.177 ± 0.012

0.7777

 

Putamen

0.159 ± 0.012

0.168 ± 0.009

0.5356

 

GP

0.151 ± 0.012

0.231 ± 0.020

0.0030

 

SN

0.282 ± 0.012

0.362 ± 0.016

0.0004

Arousal

Cortex

0.185 ± 0.008

0.253 ± 0.010

0.0001

 

Caud

0.275 ± 0.005

0.312 ± 0.006

0.0001

 

Putamen

0.273 ± 0.007

0.296 ± 0.007

0.0175

 

GP

0.262 ± 0.009

0.317 ± 0.014

0.0001

 

SN

0.433 ± 0.035

0.721 ± 0.035

0.0001

  1. Basal and histamine-stimulated [35S]GTP-γ-S binding (IOD) in the ground squirrel basal ganglia across the hibernation bout. Mid-interbout n= 3, end-interbout n= 4, hibernation n= 4, arousal n= 3. P = Student's t-test. Caud = Caudate nucleus, GP = Globus pallidus, SN Substantia nigra pars reticulata.