Comparison of the effect of histamine-stimulation on [35S]GTP-γ-S binding across the hibernation bout. Graph showing [35S]GTP-γ-S binding after histamine-stimulation compared to basal [35S]GTP-γ-S binding in the ground squirrel brain across the hibernation bout. The basal value is set at zero. Student's t-test, *P < 0.05, **P < 0.01, ***P < 0.001. Mid-interbout n= 3, end-interbout n= 4, hibernation n= 4, arousal n= 3. Caud = caudate nucleus, Put = putamen, GP = globus pallidus, SN = substantia nigra, pars reticulata. Error bars = SEM.