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Table 1 AP1 effects at the larval neuromuscular junction derive from its action in motor neurons. GAL4 drivers that include expression in motor neurons (C155, C380 and OK6) alter synaptic plasticity through either inhibition (FBZ) or activation (AP1) of AP1. Non-motor neuron drivers (Cha) or post-synaptic muscle drivers (MHC) do not achieve this effect. All numbers are raw values (+/- SEM). Numbers in the top left corner of each box are number of animals analyzed in each case. Numbers for C155 are reproduced from Sanyal et al., 2002. Abbreviations: EJC stands for evoked junctional current amplitude, mEJC for miniature evoked junctional current amplitude, and QC is quantal content of the evoked response.

From: Evidence for cell autonomous AP1 function in regulation of Drosophila motor-neuron plasticity

 

C155

C380

OK6

Cha

MHC

Control

(9)

(11)

(7)

(10)

(6)

EJC

108 +/-6

85 +/-3

139 +/-6

90 +/-6

100 +/-8

mEJC

0.76 +/-0.02

0.70 +/-0.03

0.8 +/-0.08

0.75 +/-0.06

0.89 +/-0.05

QC

142 +/-9

122 +/-8

183 +/-16

129 +/-15

115 +/-11

FBZ

(7)

(10)

(6)

(9)

(7)

EJC

80 +/-4

42 +/-6

77 +/-6

79 +/-8

102 +/-4

mEJC

0.78 +/-0.04

0.76 +/-0.05

0.66 +/-0.07

0.89 +/-0.09

0.85 +/-0.03

QC

103 +/-7

56 +/-3

120 +/-11

91 +/-8

122 +/-8

AP1

(9)

(14)

(10)

(10)

(9)

EJC

146 +/-6

121 +/-10

166 +/-11

87 +/-6

91 +/-4

mEJC

0.69 +/-0.05

0.6 +/-0.05

0.65 +/-0.03

0.75 +/-0.1

0.83 +/-0.02

QC

211 +/-12

200 +/-20

261 +/-17

127 +/-14

112 +/-7