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Table 2 Quantities of PS, SWS and W after NaCl and MCH ICV injections.

From: A role of melanin-concentrating hormone producing neurons in the central regulation of paradoxical sleep

Hours post-injection

0–2

2–4

4–6

6–8

PS

NaCl

3.4 ± 0.8

5.6 ± 1

10.8 ± 2.1

10.7 ± 2.1

 

0.02 μg

8 ± 2 *

11 ± 0.6 *

13.1 ± 2.1

9.4 ± 4.3

 

0.2 μg

10.1 ± 2.3 **

12.2 ± 2.6 *

15.6 ± 2.6

19.4 ± 3.3 *

 

1 μg

9.3 ± 2.2 **

12.5 ± 3.2 *

13.3 ± 2.4

11.3 ± 2.6

 

5 μg

5 ± 0.8

12.2 ± 2.3 **

12.4 ± 3.1

11.5 ± 2.4

 

10 μg

5.8 ± 2.3

9.5 ± 1.5

10.8 ± 3.1

10.7 ± 3.2

SWS

NaCl

23.5 ± 4.4

39.1 ± 4.8

43 ± 5.2

44.7 ± 5.6

 

0.02 μg

34.9 ± 5.8

34.6 ± 2.5

49.1 ± 2.1

39.3 ± 5.2

 

0.2 μg

39.8 ± 3.8 *

45.1 ± 7.3

51 ± 7.1

55.6 ± 7

 

1 μg

40.7 ± 7.1 *

59.2 ± 8.4 *

61.7 ± 4.6 *

56.6 ± 5.9

 

5 μg

26.8 ± 5

45.9 ± 6.4

46.7 ± 7.2

40.8 ± 4.1

 

10 μg

37.2 ± 7.8

55.4 ± 11.7

57.3 ± 3.4

51.1 ± 4.7

W

NaCl

93.5 ± 4.7

74 ± 5.4

66.9 ± 6.8

64.7 ± 7.3

 

0.02 μg

77.1 ± 7.8

74.5 ± 2.4

57.8 ± 2.3

71.3 ± 9.5

 

0.2 μg

70.1 ± 6 **

62.6 ± 7.6

53.3 ± 9.3

45 ± 9.7

 

1 μg

70.1 ± 8.6 *

48.3 ± 9 *

45 ± 5.2 *

52.1 ± 7.8

 

5 μg

91.4 ± 6.7

63.1 ± 7.4

59.7 ± 10.1

68.3 ± 5.7

 

10 μg

74.8 ± 10.6

55.2 ± 10.8

49.4 ± 2.4

56.5 ± 6.8

  1. The quantities (mean ± SEM) of PS, SWS, and W following NaCl or MCH administrations are reported in minutes per 2 hours. Significance values indicated for individual points compared to NaCl are * p < 0.05 and ** p < 0.01.