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Table 2 Quantities of PS, SWS and W after NaCl and MCH ICV injections.

From: A role of melanin-concentrating hormone producing neurons in the central regulation of paradoxical sleep

Hours post-injection 0–2 2–4 4–6 6–8
PS NaCl 3.4 ± 0.8 5.6 ± 1 10.8 ± 2.1 10.7 ± 2.1
  0.02 μg 8 ± 2 * 11 ± 0.6 * 13.1 ± 2.1 9.4 ± 4.3
  0.2 μg 10.1 ± 2.3 ** 12.2 ± 2.6 * 15.6 ± 2.6 19.4 ± 3.3 *
  1 μg 9.3 ± 2.2 ** 12.5 ± 3.2 * 13.3 ± 2.4 11.3 ± 2.6
  5 μg 5 ± 0.8 12.2 ± 2.3 ** 12.4 ± 3.1 11.5 ± 2.4
  10 μg 5.8 ± 2.3 9.5 ± 1.5 10.8 ± 3.1 10.7 ± 3.2
SWS NaCl 23.5 ± 4.4 39.1 ± 4.8 43 ± 5.2 44.7 ± 5.6
  0.02 μg 34.9 ± 5.8 34.6 ± 2.5 49.1 ± 2.1 39.3 ± 5.2
  0.2 μg 39.8 ± 3.8 * 45.1 ± 7.3 51 ± 7.1 55.6 ± 7
  1 μg 40.7 ± 7.1 * 59.2 ± 8.4 * 61.7 ± 4.6 * 56.6 ± 5.9
  5 μg 26.8 ± 5 45.9 ± 6.4 46.7 ± 7.2 40.8 ± 4.1
  10 μg 37.2 ± 7.8 55.4 ± 11.7 57.3 ± 3.4 51.1 ± 4.7
W NaCl 93.5 ± 4.7 74 ± 5.4 66.9 ± 6.8 64.7 ± 7.3
  0.02 μg 77.1 ± 7.8 74.5 ± 2.4 57.8 ± 2.3 71.3 ± 9.5
  0.2 μg 70.1 ± 6 ** 62.6 ± 7.6 53.3 ± 9.3 45 ± 9.7
  1 μg 70.1 ± 8.6 * 48.3 ± 9 * 45 ± 5.2 * 52.1 ± 7.8
  5 μg 91.4 ± 6.7 63.1 ± 7.4 59.7 ± 10.1 68.3 ± 5.7
  10 μg 74.8 ± 10.6 55.2 ± 10.8 49.4 ± 2.4 56.5 ± 6.8
  1. The quantities (mean ± SEM) of PS, SWS, and W following NaCl or MCH administrations are reported in minutes per 2 hours. Significance values indicated for individual points compared to NaCl are * p < 0.05 and ** p < 0.01.
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