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Table 2 Binding Profile of Opioid ligands in HEK-δ cells

From: Activation profiles of opioid ligands in HEK cells expressing δ opioid receptors

LIGAND AFFINITY Ki (nM)
DPDPE 0.7 ± 0.3
Fentanyl 242.5 ± 102.5
Morphine 68.5 ± 19.5
Nalbuphine 77 ± 8
Nalorphine 38.5 ± 4.0
WIN 44,441 2.6 ± 0.9
Xorphanol 1.0 ± 0.2
  1. Competition binding assays were carried out in cell homogenates of HEK-δ cells as described under Methods. Data represent mean ± SEM. of Ki values from two or more independent experiments carried out in triplicate.