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Table 2 Binding Profile of Opioid ligands in HEK-δ cells

From: Activation profiles of opioid ligands in HEK cells expressing δ opioid receptors

LIGAND

AFFINITY Ki (nM)

DPDPE

0.7 ± 0.3

Fentanyl

242.5 ± 102.5

Morphine

68.5 ± 19.5

Nalbuphine

77 ± 8

Nalorphine

38.5 ± 4.0

WIN 44,441

2.6 ± 0.9

Xorphanol

1.0 ± 0.2

  1. Competition binding assays were carried out in cell homogenates of HEK-δ cells as described under Methods. Data represent mean ± SEM. of Ki values from two or more independent experiments carried out in triplicate.
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BMC Neuroscience

ISSN: 1471-2202

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