LCSMs of rodent circumvallate taste buds double labeled with antibodies against PLCβ2 (green) and IP3R3 (red). Panels A-C are from mouse; D-F are from rat. Panels C and F represent the overlay, as described for Figure 3. Scale bar is 20 μm. Note almost complete co-localization of IP3R3 IR and PLCβ2 IR.