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Figure 3 | BMC Neuroscience

Figure 3

From: Manipulation of prenatal hormones and dietary phytoestrogens during adulthood alter the sexually dimorphic expression of visual spatial memory

Figure 3

4 Arm-Task (baited/unbaited): Number of correct arm choices, in the first four arm entries (Mean + SEM), made by female (F) and male (M) rats treated prenatally with Oil (control; A), Testosterone (B) or Flutamide (C) and fed either a Life-Long Phytoestrogen-600 diet or the Phyto-600 diet from conception and then switched postnatally to a Phyto-free diet. Phyto-free refers to animals exposed to the Phyto-600 diet from conception until 80 days of age and then placed on the Phyto-free diet from 80 days of age until sacrifice at 120 days of age. A correct choice was defined as an entry into a baited arm not yet visited in the trial. a Prenatally oil-treated females fed the Phyto-600 diet outperformed oil-treated females fed the Phyto-free diet (p < 0.05) b Prenatally oil-treated males fed the Phyto-free diet outperformed oil-treated males fed the Phyto-600 diet (p < 0.05) c Prenatally flutamide-treated males fed the Phyto-600 outperformed flutamide-treated males fed the Phyto-free diet (p < 0.05) Number of female and male animals ranged from 4 to 6 among the treatment and diet groups.

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