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Figure 3 | BMC Neuroscience

Figure 3

From: Bone morphogenetic protein-5 (BMP-5) promotes dendritic growth in cultured sympathetic neurons

Figure 3

The time course of dendritic growth is comparable between maximally effective concentrations of BMP-5 and BMP-7. Beginning on the fifth day in vitro, SCG neurons grown in the absence of glial cells were treated with control medium or medium supplemented with maximally effective concentrations of BMP-5 (300 ng/ml) or BMP-7 (50 ng/ml). After varying exposure times, cultures were fixed and immunostained with mAb to the dendritic marker MAP2. Dendritic growth was quantified with respect to the percent of cells with dendrites (A) and the number of dendrites per neuron (B). Data in panel B are expressed as the mean ± S.E.M. (n = 60 per experimental condition). There were no significant differences between BMP-7 and BMP-5 at any time point at p < 0.05.

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