Neuroprotective effect of human arginine decarboxylase (hADC) transduction against oxygen-glucose deprivation (OGD) and restoration injury. Astrocytes restored to normoxic glucose-supplied conditions after 4 hrs OGD. Cytotoxicity was assessed by the lactate dehydrogenase (LDH) assay. Data are expressed as mean of ± SD of the three different experiments performed from separate cell preparations, with triplicate determinations performed in each experiment. Asterisks indicate a p < 0.001.