Table 1 Changes in α4YFP* nAChR expression with chronic nicotine exposure in α4YFP knock-in mice in this study as compared to Nashmi et al. [7]
α4YFP* nAChR Upregulation (% of saline) | |||
|---|---|---|---|
Brain Region | Cell Type | This study | Nashmi et al. [7] |
Perforant Path | Glutamatergic | 189 ± 16 (p = 0.001) | 194 ± 2 (p < 0.001) |
Medial Habenula | Cholinergic | 114 ± 17 (ns) | 112 ± 4 (ns) |
VTA | GABAergic | 157 ± 10 (p = 0.005) | 136 ± 7 (p = 0.002) |
Dopaminergic | 92 ± 8 (ns) | 109 ± 3 (ns) | |