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Table 1 Baseline characteristics

From: Memory deficits in amyotrophic lateral sclerosis are not exclusively caused by executive dysfunction: a comparative neuropsychological study of amnestic mild cognitive impairment

Demographic variable ALS N Amnestic MCI N Healthy controls N p-value
Age at time of assessment 60.4 (12.2) 40 64.5 (5.4) 39 62.7 (10.2) 40 0.152
Male sex 65.0% (-) 40 45.0% (-) 39 69.2% (-) 40 0.063
Education (years)* 13.0 (2.5) 40 14.6 (2.8) 37 14.0 (2.1) 40 0.016
BDI-II (estimated depression scores) 7.9 (6.6) 34 6.8 (4.7) 35 4.7 (4.9) 40 0.057
ALSFRS-R 38.4 (7.8) 40 n.a. n.a. n.a.
Disease duration (in months; from symptom onset) 22.16 (19.5) 40 n.a. n.a. n.a.
Disease progression 0.54 (0.36) 40 n.a. n.a. n.a.
  1. Values are mean (SD). Two-tailed p-values of <0.05 are considered significant, shown in bold.
  2. ALS, amyotrophic lateral sclerosis; MCI, mild cognitive impairment; BDI-II, Beck Depression Inventory-II; ALSFRS-R, ALS Functional Rating Scale Revised; n.a., not applicable; disease duration, time from symptom onset to assessment; disease progression, estimated using decline in ALS Functional Rating Scale (ALSFRS-R) score since symptom onset (48-ALSFRS-R/disease duration [38]); *Years of education include: Years attended in school plus years of the longest, completed education.